Ogawa T, Dake Y, Saitoh A K, Deguchi H E, Koyanagi Y, Yamashita M, Kuroki A M, Motoda M, Amemiya T
Department of Ophthalmology, Nagasaki Municipal Hospital, Japan.
J Glaucoma. 2001 Oct;10(5):429-35. doi: 10.1097/00061198-200110000-00013.
To examine surgical effects and complications of improved nonpenetrating trabeculectomy with trabeculotomy in glaucoma patients.
Glaucoma patients in two medical institutions underwent nonpenetrating trabeculectomy with sinusotomy with or without trabeculotomy, and the results were compared retrospectively in the two groups by evaluation of final intraocular pressure, drug score, and occurrence of postsurgical complications.
Of the 63 eyes of 51 patients in this study, 31 were treated with nonpenetrating trabeculectomy with sinusotomy without trabeculotomy and 32 eyes were treated with nonpenetrating trabeculectomy with sinusotomy and trabeculotomy. The mean follow-up period was 17.0 months. The clinical features in both groups were similar in terms of age, presurgical intraocular pressure (P = 0.96), and presurgical drug score. The eyes treated with nonpenetrating trabeculectomy with sinusotomy without trabeculotomy had significantly reduced intraocular pressures from 21.0 +/- 4.3 (mean +/- SD) to 15.8 +/- 6.3 mm Hg (P = 0.0003) and drug scores from 2.4 +/- 1.2 to 1.6 +/- 1.1 without postsurgical complications. The eyes treated with nonpenetrating trabeculectomy with sinusotomy and trabeculotomy had significantly reduced intraocular pressures from 22.3 +/- 7.5 to 12.5 +/- 2.3 mm Hg (P < 0.0001) and drug scores from 2.5 +/- 1.9 to 0.9 +/- 1.3 without postsurgical complications. Thus, the eyes treated with nonpenetrating trabeculectomy with sinusotomy and trabeculotomy had significantly lower intraocular pressures (P = 0.016) and drug scores than did those treated with nonpenetrating trabeculectomy with sinusotomy without trabeculotomy.
The authors obtained satisfactory results in reducing intraocular pressure by the combination of nonpenetrating trabeculectomy, sinusotomy, and trabeculotomy.
探讨改良非穿透性小梁切除术联合小梁切开术治疗青光眼的手术效果及并发症。
两所医疗机构的青光眼患者接受了伴有或不伴有小梁切开术的鼻窦切开非穿透性小梁切除术,通过评估最终眼压、药物评分及术后并发症的发生情况,对两组结果进行回顾性比较。
本研究中51例患者的63只眼中,31只眼接受了不伴有小梁切开术的鼻窦切开非穿透性小梁切除术,32只眼接受了伴有小梁切开术的鼻窦切开非穿透性小梁切除术。平均随访期为17.0个月。两组在年龄、术前眼压(P = 0.96)和术前药物评分方面的临床特征相似。接受不伴有小梁切开术的鼻窦切开非穿透性小梁切除术的眼眼压从21.0±4.3(平均值±标准差)显著降至15.8±6.3 mmHg(P = 0.0003),药物评分从2.4±1.2降至1.6±1.1,且无术后并发症。接受伴有小梁切开术的鼻窦切开非穿透性小梁切除术的眼眼压从22.3±7.5显著降至12.5±2.3 mmHg(P < 0.0001),药物评分从2.5±1.9降至0.9±1.3,且无术后并发症。因此,接受伴有小梁切开术的鼻窦切开非穿透性小梁切除术的眼眼压(P = 0.016)和药物评分显著低于接受不伴有小梁切开术的鼻窦切开非穿透性小梁切除术的眼。
作者通过非穿透性小梁切除术、鼻窦切开术和小梁切开术联合应用,在降低眼压方面取得了满意的效果。