Watson W T, Goldsboro J A, Williams F P, Sueur R
Lab Anim Sci. 1975 Aug;25(4):459-64.
Eight-to-10-wk-old offspring of a colony of specific pathogen free [Eda:(NZW x FG)F1BR] rabbits were exposed to cultures of Pasteurella multocida and Bordetella bronchiseptica. Two groups of 9 animals each were exposed to cultures of either species of bacteria intranasally and killed 2, 7, 14, and 21 da postinoculation. Five of 9 rabbits in each group developed a mucopurulent nasal discharge 4-7 da postinoculation. The remaining 4 rabbits in each group failed to develop clinical signs. The gross and microscopic lesions did not differ in character or distribution among the inoculated rabbits. The infection was characterized by an acute upper respiratory syndrome accompanied by a mild bronchopneumonia.
将特定病原体清除的[伊顿：（新西兰白兔×弗里斯兰兔）F1BR]兔群8至10周龄的后代暴露于多杀巴斯德菌和支气管败血波氏杆菌培养物中。两组，每组9只动物，经鼻暴露于其中一种细菌培养物，并在接种后2、7、14和21天处死。每组9只兔子中有5只在接种后4至7天出现黏液脓性鼻分泌物。每组其余4只兔子未出现临床症状。接种兔子的大体和显微镜下病变在特征或分布上没有差异。感染的特征是急性上呼吸道综合征并伴有轻度支气管肺炎。
