Kimman T G, Kamp E M
Am J Vet Res. 1986 Nov;47(11):2426-30.
Infections with Bordetella bronchiseptica and Pasteurella multocida were inducted in newborn specific-pathogen-free rats. Turbinate atrophy was quantified by measuring the length of the osseous core of the ventral turbinates. Bordetella bronchiseptica readily colonized the nasal cavity. Inoculated rats developed serum agglutinating antibodies to B bronchiseptica. Turbinate atrophy, correlating with a severe inflammatory reaction, was observed after dual inoculation with B bronchiseptica or after a single inoculation when the inoculum contained relatively large numbers of B bronchiseptica. Pasteurella multocida only rarely colonized the nasal cavity, even after prior instillation of weak acetic acid solution or B bronchiseptica.
在新生的无特定病原体大鼠中引发支气管败血波氏杆菌和多杀巴斯德菌感染。通过测量腹侧鼻甲骨芯的长度对鼻甲萎缩进行量化。支气管败血波氏杆菌很容易在鼻腔定植。接种的大鼠产生了针对支气管败血波氏杆菌的血清凝集抗体。在双重接种支气管败血波氏杆菌后或当接种物中含有相对大量支气管败血波氏杆菌时单次接种后，观察到与严重炎症反应相关的鼻甲萎缩。即使在预先滴注弱乙酸溶液或支气管败血波氏杆菌后，多杀巴斯德菌也很少在鼻腔定植。
