Rohrbach S, Laskawi R
Department of Otorhinolaryngology, Head and Neck Surgery, Georg August University, Robert-Koch-Strasse 40, D-37075 Göttingen, Germany.
ORL J Otorhinolaryngol Relat Spec. 2001 Nov-Dec;63(6):382-4. doi: 10.1159/000055778.
We report on the effect of the local application of botulinum toxin A on nasal hypersecretion in a female patient with intrinsic rhinitis. 20 units of botulinum toxin A (Botox) was inserted into each nostril using a small sponge in close contact with the lower and middle turbinates. The effect was scored by the patient and by rhinomanometry. Nasal hypersecretion diminished clearly 5 days after the treatment. The rhinomanometric flow increased 2 weeks after the application. No side effects occurred. We conclude that this minimal invasive method of local botulinum toxin application might be a very effective and safe option for the treatment of nasal hypersecretion of different etiologies.
我们报告了肉毒杆菌毒素A局部应用对一名患有特发性鼻炎女性患者鼻分泌物过多的影响。使用与下鼻甲和中鼻甲紧密接触的小海绵将20单位肉毒杆菌毒素A（保妥适）插入每个鼻孔。由患者和鼻阻力测量法对效果进行评分。治疗5天后鼻分泌物过多明显减轻。应用2周后鼻阻力测量流量增加。未出现副作用。我们得出结论，这种局部应用肉毒杆菌毒素的微创方法可能是治疗不同病因鼻分泌物过多的一种非常有效且安全的选择。
