Huang Y C, Yan Y Y, Wong Y, Cheng C H
School of Nutrition, Chung Shan Medical and Dental College, Taichung, Taiwan.
Int J Vitam Nutr Res. 2001 Sep;71(5):313-8. doi: 10.1024/0300-9831.71.5.313.
Studies have indicated that vitamin B6 status decreases with age. However, little is known about vitamin B6 status of elderly people in Taiwan. The purpose of this study was to assess vitamin B6 status of elderly Taiwanese and to examine the effect of protein on various indices of vitamin B6 status in the elderly. Thirty-nine men (mean age = 69.9 +/- 4.2 years) and 55 women (mean age = 69.5 +/- 3.9 years) completed a 24-h diet recall. The mean total vitamin B6 intake (men: 1.7 +/- 0.9 g/day; women: 1.6 +/- 1.2 g/day) was higher than the 1998 US Dietary Reference Intakes (DRI) and the current Taiwan Recommended Daily Nutrient Allowance (RDNA). Dietary energy and protein intakes were not related to any vitamin B6 status parameters in any sex groups and the pooled group. Vitamin B6 intake correlated only with erythrocyte aspartate transaminase activity coefficient (EAST-AC) in the pooled (r = -0.214, p < 0.05) group. There were no significant differences in plasma pyridoxal 5'-phosphate (PLP), erythrocyte alanine transaminase activity coefficient (EALT-AC), and EAST-AC between sex groups. Although elderly subjects had adequate mean plasma PLP concentrations, 59% of men and 55% of women had plasma PLP concentrations lower than a cutoff of 20 nmol/L. The mean EALT-AC was < 1.25 in two groups with adequate vitamin B6 status. However, 23% of men and 18% of women had EALT-AC values > 1.25. The mean EAST-AC value of subjects was higher than the suggested value (< 1.8) for inadequate vitamin B6 status. The incidence of biochemical vitamin B6 deficiency in our elderly is probably more relevant from other causes than from dietary intake of protein and vitamin B6.
研究表明，维生素B6水平会随着年龄的增长而下降。然而，台湾老年人的维生素B6水平情况鲜为人知。本研究的目的是评估台湾老年人的维生素B6水平，并研究蛋白质对老年人各种维生素B6水平指标的影响。39名男性（平均年龄 = 69.9 ± 4.2岁）和55名女性（平均年龄 = 69.5 ± 3.9岁）完成了24小时饮食回顾。维生素B6的平均总摄入量（男性：1.7 ± 0.9克/天；女性：1.6 ± 1.2克/天）高于1998年美国膳食参考摄入量（DRI）和台湾现行的每日营养素推荐摄入量（RDNA）。在任何性别组和合并组中，膳食能量和蛋白质摄入量均与任何维生素B6水平参数无关。维生素B6摄入量仅与合并组中的红细胞天冬氨酸转氨酶活性系数（EAST - AC）相关（r = -0.214，p < 0.05）。性别组之间的血浆磷酸吡哆醛（PLP）、红细胞丙氨酸转氨酶活性系数（EALT - AC）和EAST - AC没有显著差异。尽管老年受试者的平均血浆PLP浓度充足，但59%的男性和55%的女性血浆PLP浓度低于20 nmol/L的临界值。在维生素B6水平充足的两组中，平均EALT - AC < 1.25。然而，23%的男性和18%的女性EALT - AC值> 1.25。受试者的平均EAST - AC值高于维生素B6水平不足的建议值（< 1.8）。我们研究中的老年人生化性维生素B6缺乏的发生率可能更多与其他原因有关，而非蛋白质和维生素B6的膳食摄入量。
