奥芬那君与氯氮平急性中毒。
Acute intoxication with orphenadrine and clozapine.
作者信息
Fucci N, Romano B, Zirilli A
机构信息
Laboratorio di Tossicologia Forense, Istituto di Medicina Legale e delle Assicurazioni, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy.
出版信息
Forensic Sci Int. 2001 Nov 15;123(1):13-6. doi: 10.1016/s0379-0738(01)00509-6.
This report describes a fatal intoxication with two different drugs: clozapine and orphenadrine. A 38-year-old man was found dead in the bedroom of his residence. Near the body were found various empty pharmaceutical boxes, employed in schizophrenic therapy, two of them containing clozapine and orphenadrine. High concentrations of clozapine and orphenadrine detected in blood, urine and gastric content were related to death. These compounds were identified and quantitated by liquid-liquid extraction followed by gas chromatographic/mass spectrometry (GC/MS) analysis.
本报告描述了一起由两种不同药物
氯氮平和奥芬那君导致的致命中毒事件。一名38岁男子被发现死于其住所的卧室。在尸体附近发现了各种用于精神分裂症治疗的空药盒，其中两个装有氯氮平和奥芬那君。在血液、尿液和胃内容物中检测到的高浓度氯氮平和奥芬那君与死亡有关。这些化合物通过液液萃取，然后进行气相色谱/质谱（GC/MS）分析进行鉴定和定量。
Zotero 插件