氯氮平所致非致命性自杀性中毒
Nonfatal suicidal intoxication by clozapine.
作者信息
Ishii A, Mizoguchi K, Kageoka M, Seno H, Kumazawa T, Suzuki O
机构信息
Hamamatsu University School of Medicine, Japan.
出版信息
J Toxicol Clin Toxicol. 1997;35(2):195-7. doi: 10.3109/15563659709001193.
CASE REPORT
A rare case of clozapine intoxication of a 23-year-old woman, who intended suicide by its overdose, but recovered under medical treatments, is presented.
METHOD
Gas chromatography/mass spectrometry and gas chromatography with nitrogen phosphorus detection were employed for its identification and quantitation, respectively.
RESULTS
Clozapine serum concentration reached 3.62 micrograms/mL 3 h after ingestion. The urine concentration 32 h after ingestion was 4.28 micrograms/mL.
病例报告
本文介绍了一例罕见的23岁女性氯氮平中毒病例，该女性过量服用氯氮平企图自杀，但经治疗后康复。
方法
分别采用气相色谱/质谱联用技术和带氮磷检测的气相色谱法进行鉴定和定量分析。
结果
摄入氯氮平3小时后，血清浓度达到3.62微克/毫升。摄入32小时后的尿液浓度为4.28微克/毫升。
Zotero 插件