Chan H H, Ying S Y, Ho W S, Wong D S, Lam L K
Division of Dermatology, Department of Medicine, University of Hong Kong.
Dermatol Surg. 2001 Nov;27(11):950-4. doi: 10.1046/j.1524-4725.2001.01048.x.
Lasers with long wavelengths are less well absorbed by melanin and are considered to be particularly suitable for hair removal in dark-skinned patients.
To compare the efficacy and complications of 800 nm diode and long-pulsed 1064 nm Nd:YAG lasers in laser-assisted hair removal in Chinese patients.
Fifteen women had hair removal treatments (13 axillae and 2 legs) with diode laser on one side and Nd:YAG laser on the other. They were followed up for 36 weeks. Subjective assessments included the degree of immediate pain and the degree of hair regrowth. Clinical photographs were taken for evaluation by two independent observers to assess complications and the degree of hair regrowth.
Long-pulsed Nd:YAG laser was found to be significantly associated with a greater degree of immediate pain after laser surgery (P =.0001, independent sample t-test) and also had a longer laser time (P =.0001, independent sample t-test). Besides transit adverse effects such as erythema and perifollicular edema, only one patient developed hypopigmentation at week 6 which resolved by week 36. Although regrowth rates were low at week 6 (subjective rates were 23% and 19% for Nd:YAG and diode laser, respectively), most patients had significant regrowth at week 36 (subjective regrowth rate 91% for both long-pulsed Nd:YAG and diode lasers).
Diode 800 nm and Nd:YAG 1064 nm lasers are safe in laser-assisted hair removal in Chinese patients, and besides immediate pain, there was no other significant adverse effect. Most patients experienced regrowth 36 weeks after a single treatment. Further study is necessary to determine the long-term clinical efficacy and complications of laser-assisted hair removal with these systems in dark-skinned patients.
长波长激光被黑色素吸收的程度较低，被认为特别适合为肤色较深的患者进行脱毛。
比较800纳米二极管激光和长脉冲1064纳米Nd:YAG激光在中国患者激光辅助脱毛中的疗效和并发症。
15名女性接受了脱毛治疗（13例腋窝和2例腿部），一侧使用二极管激光，另一侧使用Nd:YAG激光。对她们进行了36周的随访。主观评估包括即时疼痛程度和毛发再生程度。拍摄临床照片，由两名独立观察者进行评估，以评估并发症和毛发再生程度。
发现长脉冲Nd:YAG激光与激光手术后更严重的即时疼痛程度显著相关（P = 0.0001，独立样本t检验），并且激光照射时间也更长（P = 0.0001，独立样本t检验）。除了红斑和毛囊周围水肿等短暂的不良反应外，只有一名患者在第6周出现色素减退，在第36周时消退。尽管在第6周时毛发再生率较低（Nd:YAG激光和二极管激光的主观再生率分别为23%和19%），但大多数患者在第36周时出现了明显的毛发再生（长脉冲Nd:YAG激光和二极管激光的主观再生率均为91%）。
800纳米二极管激光和1064纳米Nd:YAG激光在中国患者激光辅助脱毛中是安全的，除了即时疼痛外，没有其他显著的不良反应。大多数患者在单次治疗36周后出现毛发再生。有必要进一步研究这些系统在肤色较深患者激光辅助脱毛中的长期临床疗效和并发症。
