Mittal Rachna, Sriram Snehal, Sandhu Kamaldeep
Kaya Skin Clinic, Chandigarh, India.
J Cutan Aesthet Surg. 2008 Jul;1(2):75-9. doi: 10.4103/0974-2077.44163.
LONGER WAVELENGTH LASERS SUCH AS ND: YAG are considered to be the best for darker skin phototypes.
The aim of this study was to investigate the safety and efficacy of long-pulsed, 1064 nm Nd:YAG laser-assisted hair removal in relation to multiple treatment sessions and different hair types in Indian patients.
Fifty-nine adult women with skin phototypes IV and V were treated with a long-pulsed Nd: YAG laser (1064 nm, 10 mm spot size, fluence of 30-50 J/cm(2), pulse duration 15-30 ms). Six consecutive treatment sessions were given at 4-6 week intervals. The modified Ferriman Gallway system of scoring was used to grade the hairs before each treatment session and six weeks after the last therapy. Based on this grading, three main hair types were recognised: thin vellus (Grade 1), intermediate (Grade 2), and terminal hair (Grades 3 and 4). Patients were divided into three groups: achievers who converted to thin vellus hair (Grade I), responders who shifted to a lower grade but were short of reaching grade 1, and failures who did not show any change throughout the six laser sessions.
Six weeks after six laser treatment sessions, the achievers totaled 56%, responders 23%, and failures 20% of the patient population. At the end of the 3(rd), 4(th), 5(th), and 6(th) sessions, achievers were 5, 15, 25, and 56% respectively of all the patients (P < 0.001, which was statistically significant). Achievers for terminal hair were 57.5% while it was 53.8% for intermediate hair (P = 0.9, nonsignificant). There were no permanent side effects. There were no failures in the terminal group while nearly 50% of the patients were failures in the intermediate group.
Six multiple laser treatment sessions with a long-pulsed, 1064 nm Nd: YAG laser with contact cooling were found to be safe and effective for hair reduction in Indian patients with both terminal and intermediate hair. The success rate was found to improve with successive sessions. However, terminal hairs responded better than intermediate hairs.
诸如钕钇铝石榴石（ND:YAG）等波长更长的激光被认为对肤色较深的皮肤类型最为适用。
本研究旨在探讨长脉冲1064纳米钕钇铝石榴石激光辅助脱毛在印度患者中针对多次治疗疗程及不同毛发类型的安全性和有效性。
59名IV型和V型皮肤的成年女性接受了长脉冲钕钇铝石榴石激光治疗（1064纳米，光斑大小10毫米，能量密度30 - 50焦耳/平方厘米，脉冲持续时间15 - 30毫秒）。每隔4 - 6周进行连续6次治疗疗程。采用改良的费里曼 - 高尔韦评分系统在每次治疗疗程前及最后一次治疗后6周对毛发进行分级。基于该分级，识别出三种主要毛发类型：细小毳毛（1级）、中等毛发（2级）和终毛（3级和4级）。患者被分为三组：转变为细小毳毛（1级）的成功组、转变至较低级别但未达到1级的反应组以及在整个6次激光治疗疗程中未出现任何变化的失败组。
在6次激光治疗疗程后6周，成功组占患者总数的56%，反应组占23%，失败组占20%。在第3、4、5和6次治疗疗程结束时，成功组分别占所有患者的5%、15%、25%和56%（P < 0.001，具有统计学显著性）。终毛的成功组占57.5%，中等毛发的成功组占53.8%（P = 0.9，无显著性差异）。未出现永久性副作用。终毛组无失败病例，而中等毛发组近50%的患者为失败病例。
对于印度患有终毛和中等毛发的患者，发现采用带有接触式冷却的长脉冲1064纳米钕钇铝石榴石激光进行6次多次激光治疗疗程对减少毛发是安全有效的。发现成功率随着连续疗程而提高。然而，终毛的反应比中等毛发更好。
