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实现帕金森病症状的24小时控制:运用客观指标改善夜间功能障碍

Achieving 24-hour control of Parkinson's disease symptoms: use of objective measures to improve nocturnal disability.

作者信息

Chaudhuri K R, Pal S, Bridgman K, Trenkwalder C

机构信息

Regional Movement Disorders Unit, King's College Hospital, London, UK.

出版信息

Eur Neurol. 2001;46 Suppl 1:3-10. doi: 10.1159/000058047.

DOI:10.1159/000058047
PMID:11741097
Abstract

Sleep-related problems are common in Parkinson's disease (PD) and may occur due to the disease process, alteration in sleep architecture or nocturnal motor problems such as akinesia and dystonia. Neuropsychiatric problems and nocturia can also cause significant sleep disruption in PD. Poor sleep may lead to daytime consequences such as excessive daytime sleepiness or fatigue. As there are no PD-specific sleep scales, we have devised a simple visual analogue scale - the Parkinson's disease sleep scale (PDSS) which is aimed at formal quantification of various aspects of nocturnal sleep disturbance in PD. In this paper, we discuss the development of this scale, its clinical use and how the scale could be used to devise targeted treatment strategies for nocturnal problems in PD.

摘要

睡眠相关问题在帕金森病(PD)中很常见,可能由于疾病进程、睡眠结构改变或夜间运动问题(如运动不能和肌张力障碍)而发生。神经精神问题和夜尿症也会导致PD患者严重的睡眠中断。睡眠不佳可能导致白天出现诸如日间过度嗜睡或疲劳等后果。由于没有针对PD的特定睡眠量表,我们设计了一种简单的视觉模拟量表——帕金森病睡眠量表(PDSS),旨在对PD患者夜间睡眠障碍的各个方面进行正式量化。在本文中,我们讨论了该量表的开发、其临床应用以及如何使用该量表来制定针对PD患者夜间问题的靶向治疗策略。

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