前往印度的陆路旅行者中的吸收不良情况。
Malabsorption in overland travellers to India.
作者信息
Tomkins A M, James W P, Walters J H, Cole A C
出版信息
Br Med J. 1974 Aug 10;3(5927):380-4. doi: 10.1136/bmj.3.5927.380.
Thirty-four cases of malabsorption are described in young adults after brief periods of overland travel to India. Symptoms included diarrhoea, abdominal distension, and weight loss. Investigation revealed fat, xylose, and vitamin B(12) malabsorption with marked morphological changes in the mucosa. Lower levels of serum folate and vitamin B(12) were observed in those with protracted diarrhoea, but no anaemia developed. Malabsorption may persist for many months after return to the U.K. Most patients responded initially to antibiotics, but some subsequently relapsed. The reasons why these patients developed tropical sprue are discussed.
本文描述了34例年轻人在经陆路短暂前往印度后出现吸收不良的病例。症状包括腹泻、腹胀和体重减轻。检查发现存在脂肪、木糖和维生素B12吸收不良，且黏膜有明显的形态学改变。腹泻持续时间较长的患者血清叶酸和维生素B12水平较低，但未出现贫血。回到英国后，吸收不良可能会持续数月。大多数患者最初对抗生素有反应，但有些患者随后复发。本文讨论了这些患者发生热带口炎性腹泻的原因。
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