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1
Aggregation of chlorambucil in vitro may cause misinterpretation of protein binding data.苯丁酸氮芥在体外的聚集可能会导致蛋白质结合数据的错误解读。
Br J Cancer. 1975 Jun;31(6):689-92. doi: 10.1038/bjc.1975.117.
2
In vivo and in vitro effects of tumour specific antibodies with chlorambucil.肿瘤特异性抗体与苯丁酸氮芥的体内和体外效应
Br J Cancer Suppl. 1973 Aug;1:285-98.
3
Binding of chlorambucil with antitumor globulins and its effect on drug and antibody activities.
Eur J Cancer (1965). 1976 Feb;12(2):95-100. doi: 10.1016/0014-2964(76)90211-5.
4
In vitro cytotoxicity of anti-theta (Thy-1) antibodies combined with chlorambucil.抗θ（Thy-1）抗体与苯丁酸氮芥联合应用的体外细胞毒性。
Immunology. 1975 Feb;28(2):323-9.
5
The conjugation of chlorambucil with human gamma-globulin.苯丁酸氮芥与人γ-球蛋白的结合。
Chem Biol Interact. 1975 Mar;10(3):169-72. doi: 10.1016/0009-2797(75)90110-6.
6
Potentiation of the in vitro cytotoxicity of chlorambucil by monoclonal antibodies.单克隆抗体增强苯丁酸氮芥的体外细胞毒性
J Immunol. 1986 Nov 15;137(10):3361-6.
7
Suppression of an AKR lymphoma by antibody and chlorambucil.抗体与苯丁酸氮芥对AKR淋巴瘤的抑制作用
J Natl Cancer Inst. 1975 Dec;55(6):1353-7. doi: 10.1093/jnci/55.6.1353.
8
[Serological reaction used in the physiopathological study of neoplasms. VII. Characterization of the serologically-active fraction].[用于肿瘤生理病理学研究的血清学反应。VII. 血清学活性成分的特性鉴定]
Boll Soc Ital Biol Sper. 1977 May 15;53(9):710-3.
9
[Drug targeting with allogeneic IgG in patients with disseminated neuroblastoma].[异基因IgG在播散性神经母细胞瘤患者中的药物靶向治疗]
Clin Ter. 1984 Aug 15;110(3):203-8.
10
Tumor-bound immunoglobulins: their possible role in circumventing antitumor immunity.肿瘤结合免疫球蛋白：它们在规避抗肿瘤免疫中的可能作用。
Johns Hopkins Med J Suppl. 1974;3:289-300.

引用本文的文献

1
Oncostatic-antibody complexes in chemotherapy.化疗中的肿瘤生长抑制抗体复合物
Cancer Chemother Pharmacol. 1980;4(1):29-32. doi: 10.1007/BF00255454.
2
A chlorambucil-anti-CEA conjugate cytotoxic for human colon adenocarcinoma cells in vitro.一种苯丁酸氮芥-抗癌胚抗原缀合物，在体外对人结肠腺癌细胞具有细胞毒性。
Br J Cancer. 1984 Feb;49(2):245-6. doi: 10.1038/bjc.1984.38.
3
Stability of solutions of antineoplastic agents during preparation and storage for in vitro assays. General considerations, the nitrosoureas and alkylating agents.用于体外测定的抗肿瘤药物制剂在制备和储存过程中的稳定性。一般考虑因素、亚硝基脲类和烷化剂。
Cancer Chemother Pharmacol. 1985;14(2):83-95. doi: 10.1007/BF00434343.

本文引用的文献

1
The effect of macromolecules upon the rates of hydrolysis of aromatic nitrogen mustard derivatives.大分子对芳香族氮芥衍生物水解速率的影响。
Chem Biol Interact. 1971 Dec;4(1):31-9. doi: 10.1016/0009-2797(71)90031-7.
2
Factors affecting the noncovalent binding of chlorambucil to rabbit immunoglobulin G.影响苯丁酸氮芥与兔免疫球蛋白G非共价结合的因素。
Cancer Res. 1974 Apr;34(4):882-5.
3
The cure and concomitant immunization of mice bearing Ehrlich ascites tumors by treatment with an antibody--alkylating agent complex.用抗体-烷化剂复合物治疗携带艾氏腹水瘤的小鼠的治愈及伴随免疫作用
Eur J Cancer (1965). 1973 Oct;9(10):741-5. doi: 10.1016/0014-2964(73)90065-0.
4
Immunochemotherapy of cancer with chlorambucil-carrying antibody.用携带苯丁酸氮芥的抗体对癌症进行免疫化疗。
Br Med J. 1972 Aug 26;3(5825):495-9. doi: 10.1136/bmj.3.5825.495.
5
Antibody as carrier of chlorambucil.抗体作为苯丁酸氮芥的载体。
Cancer. 1972 May;29(5):1398-400. doi: 10.1002/1097-0142(197205)29:5<1398::aid-cncr2820290542>3.0.co;2-d.
6
In vivo and in vitro effects of tumour specific antibodies with chlorambucil.肿瘤特异性抗体与苯丁酸氮芥的体内和体外效应
Br J Cancer Suppl. 1973 Aug;1:285-98.
7
Augmentation of cytotoxic drug action by antibodies directed at cell surface.
Nature. 1974 Mar 1;248(5443):81-2. doi: 10.1038/248081a0.
8
Protection of mice against syngeneic lymphomata: II. Collaboration between drugs and antibodies.小鼠同基因淋巴瘤的防护：II. 药物与抗体之间的协同作用
Br J Cancer. 1974 Oct;30(4):305-11. doi: 10.1038/bjc.1974.197.
9
The interaction of chlorambucil with human gamma-globulin.苯丁酸氮芥与人γ球蛋白的相互作用。
Chem Biol Interact. 1974 Apr;8(4):261-7. doi: 10.1016/0009-2797(74)90034-9.

Aggregation of chlorambucil in vitro may cause misinterpretation of protein binding data.

作者信息

Blakeslee D, Chen M, Kennedy J C

出版信息

Br J Cancer. 1975 Jun;31(6):689-92. doi: 10.1038/bjc.1975.117.

DOI:10.1038/bjc.1975.117
PMID:1174447
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2009484/
Abstract
摘要