Winyard P, Chitty L
Paediatric Clinical Sciences, Institute of Child Health, 30 Guildford Street, London WC1N 6EH, UK.
Prenat Diagn. 2001 Nov;21(11):924-35. doi: 10.1002/pd.208.
Cystic and bright kidneys can pose a significant diagnostic dilemma when discovered as an incidental finding at the time of a routine fetal ultrasound scan. There are diverse aetiologies with equally variable implications for the prognosis in the affected fetus, and for future pregnancies. Accurate antenatal diagnosis in the absence of any positive family history is often not possible and a team approach to management (to include the fetal medicine specialist, paediatric nephrologist or urologist, geneticists and in some cases, pathologist) is essential. In this review we will attempt to describe the embryology and aetiology of these conditions and suggest an approach to management.
在常规胎儿超声扫描时偶然发现的囊性和明亮的肾脏,可能会带来重大的诊断难题。其病因多样,对受影响胎儿的预后以及未来妊娠的影响也同样各不相同。在没有任何阳性家族史的情况下,往往无法进行准确的产前诊断,因此采用团队管理方法(包括胎儿医学专家、儿科肾病学家或泌尿科医生、遗传学家,在某些情况下还包括病理学家)至关重要。在这篇综述中,我们将试图描述这些病症的胚胎学和病因,并提出一种管理方法。