King D W, Gurry J F, Brooke B N
Br J Surg. 1975 Aug;62(8):645-6. doi: 10.1002/bjs.1800620816.
The evidence for the value of noxytiolin (Noxyflex) in peritonitis is contradictory. In a controlled trial of the effect of noxytiolin in pertonitis in rabbits we have found a significant increase in mortality in the trial group compared with a control group, but no significant difference when a dose equivalent to the recommended human dose is used. The postoperative course is adversely affected in the animals receiving noxytiolin.
诺昔硫脲(Noxyflex)在腹膜炎治疗中的价值证据相互矛盾。在一项关于诺昔硫脲对兔腹膜炎影响的对照试验中,我们发现试验组的死亡率与对照组相比显著增加,但使用相当于推荐人体剂量时无显著差异。接受诺昔硫脲的动物术后病程受到不利影响。