Loganovsky K N, Yuryev K L
Department of Neurology, Research Centre for Radition Medicine of Academy of Medical Sciences of Ukraine, Kiev.
J Neuropsychiatry Clin Neurosci. 2001 Fall;13(4):441-58. doi: 10.1176/jnp.13.4.441.
Prospective conventional EEG study was carried out 3-5 and 10-13 years after the Chernobyl accident (1986) in patients who had acute radiation sickness and in emergency workers in 1986 ("liquidators"). Control groups comprised healthy volunteers; veterans of the Afghanistan war with posttraumatic stress disorder; veterans with mild traumatic brain injury; and patients with dyscirculatory encephalopathy. In 3-5 years after irradiation, there were irritated EEG changes with paroxysmal activity shifted to the left frontotemporal region (cortical-limbic overactivation) that were transformed 10-13 years after irradiation toward a low-voltage EEG pattern with excess of fast (beta) and slow (delta) activity together with depression of alpha and theta activity (organic brain damage with inhibition of the cortical-limbic system). Quantitative EEG is likely to be very informative for investigation of dose-effect relationships.
对1986年切尔诺贝利事故后3 - 5年以及10 - 13年的急性放射病患者和1986年的应急工作人员（“清理者”）进行了前瞻性常规脑电图研究。对照组包括健康志愿者、患有创伤后应激障碍的阿富汗战争退伍军人、轻度创伤性脑损伤退伍军人以及循环障碍性脑病患者。照射后3 - 5年，脑电图出现刺激性改变，阵发性活动转移至左额颞区（皮质 - 边缘系统过度激活），照射后10 - 13年转变为低电压脑电图模式，伴有快速（β）和慢速（δ）活动增加以及α和θ活动抑制（皮质 - 边缘系统受抑制的器质性脑损伤）。定量脑电图可能对研究剂量 - 效应关系非常有帮助。
