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替代磁场暴露指标:在一项白血病生存研究中与时间加权平均值、电器使用及儿童人口统计学特征的关系

Alternative magnetic field exposure metrics: relationship to TWA, appliance use, and demographic characteristics of children in a leukemia survival study.

作者信息

Foliart D E, Iriye R N, Tarr K J, Silva J M, Kavet R, Ebi K L

机构信息

Public Health Institute, Berkeley, California, USA.

出版信息

Bioelectromagnetics. 2001 Dec;22(8):574-80. doi: 10.1002/bem.86.

Abstract

The ongoing Childhood Leukemia Survival Study is examining the possible association between magnetic field exposure and survival of children with newly diagnosed acute lymphocytic leukemia (ALL). We report the results of the first year 24 h personal magnetic field monitoring for 356 US and Canadian children by time weighted average TWA and alternative exposure metrics. The mean TWA of 0.12 microT was similar to earlier personal exposure studies involving children. A high correlation was found between 24 h TWA and alternative metrics: 12 h day TWA, 12 night TWA, geometric mean, 95th percentile value, percentage time over 0.2 and 0.3 microT, and an estimate of field stability (Constant Field Metric). Two measures of field intermittency, rate of change metric (RCM) and standardized rate of change metric (RCMS), were not highly correlated with TWA. The strongest predictor of TWA was location of residence, with highest TWAs associated with urban areas. Residence in an apartment, lower paternal educational level, and residential mobility were also associated with higher TWAs. There were no significant differences in the appliance use patterns of children with higher TWA values. Children with the highest field intermittency (high RCM) were more likely to sit within 3 feet of a video game attached to the TV. Our results suggest that 24 h TWA is a representative metric for certain patterns of exposure, but is not highly correlated with two metrics that estimate field intermittency.

摘要

正在进行的儿童白血病生存研究正在调查磁场暴露与新诊断的急性淋巴细胞白血病(ALL)患儿生存率之间的可能关联。我们报告了对356名美国和加拿大儿童进行的第一年24小时个人磁场监测结果,采用时间加权平均值(TWA)和其他暴露指标。0.12微特斯拉的平均TWA与早期涉及儿童的个人暴露研究相似。发现24小时TWA与其他指标之间存在高度相关性:12小时白天TWA、12小时夜间TWA、几何平均值、第95百分位数、超过0.2和0.3微特斯拉的时间百分比,以及场稳定性估计值(恒定场指标)。两种场间歇性测量方法,变化率指标(RCM)和标准化变化率指标(RCMS),与TWA的相关性不高。TWA的最强预测因素是居住地点,城市地区的TWA最高。居住在公寓、父亲教育水平较低和居住流动性也与较高的TWA相关。TWA值较高的儿童在电器使用模式上没有显著差异。场间歇性最高(高RCM)的儿童更有可能坐在连接电视的视频游戏设备3英尺范围内。我们的结果表明,24小时TWA是某些暴露模式的代表性指标,但与估计场间歇性的两个指标相关性不高。

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