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波兰中东部农村和城市地区葡萄膜炎的病因

Etiology of uveitis in rural and urban areas of mid-eastern Poland.

作者信息

Biziorek B, Mackiewicz J, Zagórski Z, Krwawicz L, Haszcz D

机构信息

1st Department of Ophthalmology, Medical Academy, Lublin, Poland.

出版信息

Ann Agric Environ Med. 2001;8(2):241-3.

PMID:11748883
Abstract

The aim of this study was to assess and compare the frequencies of uveitis etiology in inhabitants of rural and urban areas of mid-eastern Poland. We reviewed the cases of 563 patients (263 males, 300 females; aged 2-87) with uveitis, treated at the 1st Department of Ophthalmology at the Medical Academy in Lublin and at the District Ophthalmic Hospital in Kielce, Poland, from January 1996-December 2000. Anatomical classification of uveitis was used according to the International Uveitis Study Group and etiological classification including uveitis associated with trauma, infection, systemic disease, non-associated with a systemic disease and masquerade syndromes. Data regarding age, gender, place of residence, anatomical location and etiology of uveitis were obtained. Statistical analyses were performed using Pearson's chi-square test, Spearman's rank correlation test and logistic regression. Etiology of uveitis was established in 70.0% of cases. The most common cause of uveitis was infection. Patients from rural areas were significantly more likely to have uveitis of infectious origin whereas patients from urban areas significantly more likely to have uveitis associated with a systemic disease. In conclusion, the pattern of uveitis in mid-eastern Poland confirms the influence of environmental factors on the etiology of this heterogenous disease.

摘要

本研究旨在评估和比较波兰中东部农村和城市地区居民葡萄膜炎病因的发生率。我们回顾了1996年1月至2000年12月期间在波兰卢布林医科大学第一眼科和凯尔采地区眼科医院接受治疗的563例葡萄膜炎患者(男263例,女300例;年龄2 - 87岁)的病例。根据国际葡萄膜炎研究组的标准进行葡萄膜炎的解剖学分类,并进行病因学分类,包括与创伤、感染、全身性疾病相关的葡萄膜炎、与全身性疾病无关的葡萄膜炎以及伪装综合征。获取了有关葡萄膜炎患者的年龄、性别、居住地点、解剖位置和病因的数据。使用Pearson卡方检验、Spearman秩相关检验和逻辑回归进行统计分析。在70.0%的病例中确定了葡萄膜炎的病因。葡萄膜炎最常见的病因是感染。农村地区的患者患感染性葡萄膜炎的可能性显著更高,而城市地区的患者患与全身性疾病相关的葡萄膜炎的可能性显著更高。总之,波兰中东部葡萄膜炎的模式证实了环境因素对这种异质性疾病病因的影响。

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