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枯草芽孢杆菌基因组参考数据库:枯草芽孢杆菌列表

SubtiList: the reference database for the Bacillus subtilis genome.

作者信息

Moszer Ivan, Jones Louis M, Moreira Sandrine, Fabry Cécilia, Danchin Antoine

机构信息

Unité de Génétique des Génomes Bactériens and Logiciels et Banques de Données, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France.

出版信息

Nucleic Acids Res. 2002 Jan 1;30(1):62-5. doi: 10.1093/nar/30.1.62.

Abstract

SubtiList is the reference database dedicated to the genome of Bacillus subtilis 168, the paradigm of Gram-positive endospore-forming bacteria. Developed in the framework of the B.subtilis genome project, SubtiList provides a curated dataset of DNA and protein sequences, combined with the relevant annotations and functional assignments. Information about gene functions and products is continuously updated by linking relevant bibliographic references. Recently, sequence corrections arising from both systematic verifications and submissions by individual scientists were included in the reference genome sequence. SubtiList is based on a generic relational data schema and a World Wide Web interface developed for the handling of bacterial genomes, called GenoList. The World Wide Web interface was designed to allow users to easily browse through genome data and retrieve information according to common biological queries. SubtiList also provides more elaborate tools, such as pattern searching, which are tightly connected to the overall browsing system. SubtiList is accessible at http://genolist.pasteur.fr/SubtiList/. Similar bacterial databases are accessible at http://genolist.pasteur.fr/.

摘要

枯草芽孢杆菌列表(SubtiList)是一个专门针对枯草芽孢杆菌168基因组的参考数据库,枯草芽孢杆菌168是革兰氏阳性产芽孢细菌的范例。SubtiList是在枯草芽孢杆菌基因组计划的框架内开发的,它提供了一个经过整理的DNA和蛋白质序列数据集,并结合了相关的注释和功能分配。通过链接相关的文献参考,关于基因功能和产物的信息会不断更新。最近,由系统验证和个别科学家提交所产生的序列校正已包含在参考基因组序列中。SubtiList基于一个通用的关系数据模式和一个为处理细菌基因组而开发的万维网界面,称为GenoList。万维网界面的设计目的是让用户能够轻松浏览基因组数据,并根据常见生物学问题检索信息。SubtiList还提供了更精细的工具,如模式搜索,这些工具与整体浏览系统紧密相连。可通过http://genolist.pasteur.fr/SubtiList/访问SubtiList。类似的细菌数据库可通过http://genolist.pasteur.fr/访问。

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