人类（PEDB）和小鼠（mPEDB）前列腺表达数据库。
The human (PEDB) and mouse (mPEDB) Prostate Expression Databases.
作者信息
Nelson Peter S, Pritchard Colin, Abbott Denise, Clegg Nigel
机构信息
Division of Human Biology and Division of Clinical Research, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, WA 98109-1024, USA.
出版信息
Nucleic Acids Res. 2002 Jan 1;30(1):218-20. doi: 10.1093/nar/30.1.218.
The Prostate Expression Databases (PEDB and mPEDB) are online resources designed to allow researchers to access and analyze gene expression information derived from the human and murine prostate, respectively. Human PEDB archives more than 84 000 Expressed Sequence Tags (ESTs) from 38 prostate cDNA libraries in a curated relational database that provides detailed library information including tissue source, library construction methods, sequence diversity and sequence abundance. The differential expression of each EST species can be viewed across all libraries using a Virtual Expression Analysis Tool (VEAT), a graphical user interface written in Java for intra- and inter-library sequence comparisons. Recent enhancements to PEDB include (i) the development of a murine prostate expression database, mPEDB, that complements the human gene expression information in PEDB, (ii) the assembly of a non-redundant sequence set or 'prostate unigene' that represents the diversity of gene expression in the prostate, and (iii) an expanded search tool that supports both text-based and BLAST queries. PEDB and mPEDB are accessible via the World Wide Web at http://www.pedb.org and http://www.mpedb.org.
前列腺表达数据库（PEDB和mPEDB）是在线资源，旨在分别让研究人员获取和分析源自人类和小鼠前列腺的基因表达信息。人类PEDB在一个经过整理的关系数据库中存档了来自38个前列腺cDNA文库的84000多个表达序列标签（EST），该数据库提供详细的文库信息，包括组织来源、文库构建方法、序列多样性和序列丰度。使用虚拟表达分析工具（VEAT）可以查看所有文库中每个EST种类的差异表达，VEAT是一个用Java编写的图形用户界面，用于库内和库间的序列比较。PEDB最近的改进包括：（i）开发了小鼠前列腺表达数据库mPEDB，它补充了PEDB中的人类基因表达信息；（ii）组装了一个代表前列腺基因表达多样性的非冗余序列集或“前列腺单基因”；（iii）一个扩展的搜索工具，支持基于文本和BLAST查询。可通过万维网在http://www.pedb.org和http://www.mpedb.org访问PEDB和mPEDB。
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