Rencüzoğullari Eyyüp, Ila Hasan Basri, Topaktaş Mehmet, Kayraldiz Ahmet, Budak Songül, Arslan Mehmet
Cukurova University, Faculty of Arts and Sciences, Biology Department, Adana, Turkey.
Teratog Carcinog Mutagen. 2002;22(1):51-8. doi: 10.1002/tcm.1038.
In this study, the chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) were investigated in human lymphocytes treated with spiramycin antibiotic (trade name, rovamycin). Spiramycin did not induce the CAs and SCEs, and also did not decrease the mitotic index (MI). However, spiramycin decreased the replication index (RI) only at 48 h treatment times.
在本研究中，对用螺旋霉素抗生素（商品名，罗华密新）处理的人淋巴细胞中的染色体畸变（CAs）和姐妹染色单体交换（SCEs）进行了研究。螺旋霉素未诱导CAs和SCEs，也未降低有丝分裂指数（MI）。然而，螺旋霉素仅在处理48小时时降低了复制指数（RI）。
