van Lommel P, van Wees R, Meyers V, Elfferich I
Division of Cardiology, Hospital Rijnstate, Arnhem, Netherlands.
Lancet. 2001 Dec 15;358(9298):2039-45. doi: 10.1016/S0140-6736(01)07100-8.
Some people report a near-death experience (NDE) after a life-threatening crisis. We aimed to establish the cause of this experience and assess factors that affected its frequency, depth, and content.
In a prospective study, we included 344 consecutive cardiac patients who were successfully resuscitated after cardiac arrest in ten Dutch hospitals. We compared demographic, medical, pharmacological, and psychological data between patients who reported NDE and patients who did not (controls) after resuscitation. In a longitudinal study of life changes after NDE, we compared the groups 2 and 8 years later.
62 patients (18%) reported NDE, of whom 41 (12%) described a core experience. Occurrence of the experience was not associated with duration of cardiac arrest or unconsciousness, medication, or fear of death before cardiac arrest. Frequency of NDE was affected by how we defined NDE, the prospective nature of the research in older cardiac patients, age, surviving cardiac arrest in first myocardial infarction, more than one cardiopulmonary resuscitation (CPR) during stay in hospital, previous NDE, and memory problems after prolonged CPR. Depth of the experience was affected by sex, surviving CPR outside hospital, and fear before cardiac arrest. Significantly more patients who had an NDE, especially a deep experience, died within 30 days of CPR (p<0.0001). The process of transformation after NDE took several years, and differed from those of patients who survived cardiac arrest without NDE.
We do not know why so few cardiac patients report NDE after CPR, although age plays a part. With a purely physiological explanation such as cerebral anoxia for the experience, most patients who have been clinically dead should report one.
一些人在经历危及生命的危机后会报告濒死体验(NDE)。我们旨在确定这种体验的原因,并评估影响其频率、深度和内容的因素。
在一项前瞻性研究中,我们纳入了荷兰十家医院连续344例心脏骤停后成功复苏的心脏病患者。我们比较了复苏后报告有濒死体验的患者与未报告濒死体验的患者(对照组)之间的人口统计学、医学、药理学和心理学数据。在一项关于濒死体验后生活变化的纵向研究中,我们在2年和8年后对两组进行了比较。
62例患者(18%)报告有濒死体验,其中41例(12%)描述了核心体验。这种体验的发生与心脏骤停或昏迷的持续时间、药物治疗或心脏骤停前对死亡的恐惧无关。濒死体验的频率受我们对濒死体验的定义、老年心脏病患者研究的前瞻性性质、年龄、首次心肌梗死时心脏骤停存活、住院期间多次心肺复苏(CPR)、既往濒死体验以及长时间心肺复苏后的记忆问题影响。体验的深度受性别、院外心肺复苏存活以及心脏骤停前的恐惧影响。有濒死体验,尤其是深度体验的患者,在心肺复苏后30天内死亡的人数明显更多(p<0.0001)。濒死体验后的转变过程需要数年时间,且与未经历濒死体验而心脏骤停存活的患者不同。
我们不知道为什么心肺复苏后如此少的心脏病患者报告有濒死体验,尽管年龄起到了一定作用。对于这种体验,若用诸如脑缺氧这样纯粹的生理学解释,大多数临床死亡的患者都应该报告有濒死体验。