Potter Michael J, Szabo Shelagh M, Chan Eleanor Y, Morris Andrew H C
Department of Ophthalmology, University of British Columbia, Vancouver, British Columbia, Canada.
Am J Ophthalmol. 2002 Jan;133(1):149-51. doi: 10.1016/s0002-9394(01)01205-3.
To report the outcome of a patient with a subretinal neovascular membrane secondary to idiopathic juxtafoveolar retinal telangiectasis treated with photodynamic female therapy.
Interventional case report. A 43-year-old female with type 2A idiopathic juxtafoveolar retinal telangiectasis presented with a 2-week history of decreased vision and a subretinal neovascular membrane in the left eye.
Visual improvement from 20/70-2 to 20/50-2 in the left eye was observed after two photodynamic therapy treatments of a juxtafoveal subretinal neovascular membrane with verteporfin, and was maintained through 7 months of follow-up. Fluorescein angiography showed no leakage specific to the subretinal neovascular membrane, but leakage from the juxtafoveal telangiectasis continued.
A substantial improvement was seen in this patient after treatment of the juxtafoveal subretinal neovascular membrane by photodynamic therapy. Given the poor prognosis of these lesions, photodynamic therapy may therefore be a useful treatment for patients with subretinal neovascular membranes associated with idiopathic juxtafoveolar retinal telangiectasis.
报告1例继发于特发性黄斑旁视网膜毛细血管扩张症的视网膜下新生血管膜患者接受光动力疗法治疗的结果。
介入性病例报告。1例患有2A型特发性黄斑旁视网膜毛细血管扩张症的43岁女性,左眼视力下降2周,伴有视网膜下新生血管膜。
在用维替泊芬对黄斑旁视网膜下新生血管膜进行两次光动力治疗后,观察到左眼视力从20/70-2提高到20/50-2,并在7个月的随访中保持稳定。荧光素血管造影显示视网膜下新生血管膜无特异性渗漏,但黄斑旁毛细血管扩张仍有渗漏。
该患者经光动力疗法治疗黄斑旁视网膜下新生血管膜后有显著改善。鉴于这些病变预后较差,因此光动力疗法可能是治疗与特发性黄斑旁视网膜毛细血管扩张症相关的视网膜下新生血管膜患者的一种有效治疗方法。