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光动力疗法联合玻璃体内注射曲安奈德治疗双侧特发性黄斑旁毛细血管扩张症的视网膜下新生血管

Photodynamic therapy and intravitreal triamcinolone for a subretinal neovascularization in bilateral idiopathic juxtafoveal telangiectasis.

作者信息

Smithen Lindsay M, Spaide Richard F

机构信息

Vitreous, Retina, Macula Consultants of New York, New York, USA.

出版信息

Am J Ophthalmol. 2004 Nov;138(5):884-5. doi: 10.1016/j.ajo.2004.05.073.

Abstract

PURPOSE

To report combined treatment of photodynamic therapy (PDT) with verteporfin and intravitreal triamcinolone acetonide injection for subfoveal neovascularization secondary to bilateral idiopathic juxtafoveal telangiectasis.

DESIGN

Interventional case report.

METHOD

A patient with a subfoveal neovascularization secondary to bilateral idiopathic juxtafoveal telangiectasis was treated with PDT plus an intravitreal injection of 4 mg of triamcinolone acetonide.

RESULTS

Leakage in the late-phase of fluorescein angiography resolved with attenuation of telangiectatic vessels and improvement in visual acuity from 20/200 to 20/50. At 9 months post-treatment, recurrent leakage was treated with repeat PDT and intravitreal triamcinolone. One year after initial presentation, visual acuity was 20/60 with no leakage on fluorescein.

CONCLUSION

Combined treatment with PDT and intravitreal triamcinolone acetonide resulted in regression of a subfoveal neovascular membrane and improvement in visual acuity during the course of follow-up.

摘要

目的

报告用维替泊芬光动力疗法(PDT)联合玻璃体内注射曲安奈德治疗双侧特发性近黄斑部毛细血管扩张继发的黄斑下新生血管。

设计

介入性病例报告。

方法

一名双侧特发性近黄斑部毛细血管扩张继发黄斑下新生血管的患者接受了PDT联合玻璃体内注射4mg曲安奈德治疗。

结果

荧光素血管造影晚期渗漏消失,毛细血管扩张血管变细,视力从20/200提高到20/50。治疗后9个月,复发性渗漏通过重复PDT和玻璃体内注射曲安奈德治疗。初次就诊一年后,视力为20/60,荧光素检查无渗漏。

结论

PDT与玻璃体内注射曲安奈德联合治疗导致黄斑下新生血管膜消退,并在随访过程中提高了视力。

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