Brouwer A F, van Gils J F, Brand P L, de Graaf J H
Isala Klinieken, locaties Weezenlanden en Sophia, afd. Kindergeneeskunde, Postbus 10.500, 8000 GM Zwolle.
Ned Tijdschr Geneeskd. 2001 Nov 24;145(47):2257-9.
Two infants, a girl, aged four weeks, and a boy, aged three weeks, came to our attention with poor feeding and weight loss. Later the typical cough of pertussis appeared. Serological testing confirmed that both patients' mothers had recently had pertussis. One mother suffered from severe and typical coughing periods even throughout labour. Despite the vaccination program in the Netherlands, each year new-born infants with pertussis require hospitalisation. Pertussis during the neonatal period is seldom described. Adults can suffer from pertussis, even when they have been vaccinated in childhood. They then become contagious for unvaccinated infants. Pertussis during the neonatal period is an insidious disease with sometimes severe complications. If pertussis is suspected in mothers with new-born infants or pregnant women towards the end of the pregnancy, they should be treated with antibiotics to prevent pertussis in the new-born infant.
两名婴儿引起了我们的注意,一名四周大的女婴和一名三周大的男婴,他们出现喂养困难和体重减轻的情况。后来出现了百日咳的典型咳嗽症状。血清学检测证实,两名患者的母亲最近都患过百日咳。其中一位母亲甚至在整个分娩过程中都经历了严重且典型的咳嗽期。尽管荷兰有疫苗接种计划,但每年仍有患百日咳的新生儿需要住院治疗。新生儿期的百日咳很少被描述。成年人即使在儿童时期接种过疫苗,也可能患百日咳。然后他们会将疾病传染给未接种疫苗的婴儿。新生儿期的百日咳是一种隐匿性疾病,有时会引发严重并发症。如果在新生儿母亲或接近妊娠末期的孕妇中怀疑患有百日咳,应使用抗生素进行治疗,以预防新生儿感染百日咳。