Department of Microbiology & Infection Control Unit, Norfolk & Norwich University Teaching Hospital, Norwich, UK.
J Hosp Infect. 2012 Oct;82(2):133-5. doi: 10.1016/j.jhin.2012.07.012. Epub 2012 Aug 31.
Bordetella pertussis, the cause of whooping cough, is highly contagious. A female, twin 1, born at 34 weeks of gestation and present on a neonatal intensive care unit for 19 days, became apnoeic and bradycardic. A pernasal swab, sent when pertussis was clinically suspected, grew B. pertussis. Twin 2 had similar symptoms. The mother admitted having a prolonged cough. Polymerase chain reaction of pernasal swabs was positive for both twins, and the mother had positive pertussis serology. An incident management committee was convened. Fifty neonates and 117 healthcare workers were identified as contacts and were offered information, azithromycin chemoprophylaxis and/or pertussis vaccination according to UK national guidelines.
百日咳鲍特菌是百日咳的病原体，具有高度传染性。一名 34 周早产的双胞胎女婴 1 号在新生儿重症监护病房住院 19 天，出现呼吸暂停和心动过缓。当临床怀疑百日咳时，进行了经鼻拭子采样，结果培养出百日咳鲍特菌。双胞胎 2 号出现了类似的症状。母亲承认自己有长时间的咳嗽。对双胞胎的经鼻拭子进行聚合酶链反应检测均为阳性，母亲的百日咳血清学检测也为阳性。成立了一个事件管理委员会。根据英国国家指南，确定了 50 名新生儿和 117 名医护人员为接触者，并为他们提供了信息、阿奇霉素化学预防和/或百日咳疫苗接种。
