Beiter A, Lewis K, Pineda E F, Cherry J D
Department of Pediatrics, UCLA Medical Center, School of Medicine, University of California.
Obstet Gynecol. 1993 Oct;82(4 Pt 2 Suppl):691-3.
Pertussis is an illness that is frequently unrecognized in adults. The source of pertussis infection in young infants is usually an adult and most frequently a parent.
A woman developed severe paroxysmal coughing requiring hospitalization 6 days before delivery. She was thought to have viral pneumonia and reactive airway disease. One week after birth, her infant developed a similar illness and also required hospitalization. The infant's respiratory illness progressively worsened, resulting in death.
Although the clinical findings were typical for pertussis in both the mother and infant, pertussis was not considered and therefore neither received specific antimicrobial therapy. Patients with illnesses suggestive of pertussis, and their contacts, should be treated with erythromycin before the results of laboratory studies are known, in order to prevent serious and fatal illnesses in infants.
百日咳在成年人中常未被识别。幼儿百日咳感染的来源通常是成年人,且最常见的是父母。
一名妇女在分娩前6天出现严重阵发性咳嗽,需要住院治疗。她被认为患有病毒性肺炎和反应性气道疾病。出生一周后,她的婴儿也出现了类似疾病,同样需要住院。婴儿的呼吸道疾病逐渐恶化,最终死亡。
尽管母亲和婴儿的临床表现均符合百日咳,但未考虑百日咳诊断,因此均未接受特异性抗菌治疗。对于疑似百日咳的患者及其接触者,在实验室检查结果出来之前,应使用红霉素进行治疗,以预防婴儿出现严重和致命疾病。