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GPT系统在亲子鉴定案件中的应用。

Application of the GPT system in paternity cases.

作者信息

Olaisen B

出版信息

Hum Hered. 1975;25(3):204-17. doi: 10.1159/000152727.

DOI:10.1159/000152727
PMID:1176154
Abstract

Experiments show that the GPT starch gel pattern of any given blood sample is fully reproducible, and that an individual's GPT type is constant at least after the age of 1 month. GPT isoenzyme patterns are influenced and may be changed during storage of unfrozen blood. The interval between sampling and preparation of haemolysate should therefore not exceed 4 days. In haemolysates kept at -25 degrees C the isoenzyme patterns remain unchanged for at least many months. The GPT system forms a valuable means for statistical information in paternity cases. Thus, the overall chance is 18.7% for paternity exclusion or strong evidence against paternity for a falsely alleged father. Based on a material of 1,316 paternity cases, it is concluded that the GPT system is a valuable supplement to other systems of genetic markers in cases of disputed paternity.

摘要

实验表明,任何给定血样的GPT淀粉凝胶图谱均可完全重现,而且个体的GPT类型至少在1个月龄后保持恒定。GPT同工酶图谱会受到影响,并且在未冷冻血液储存期间可能会发生变化。因此,采样与制备溶血产物之间的间隔不应超过4天。保存在-25摄氏度的溶血产物中,同工酶图谱至少在许多个月内保持不变。GPT系统是亲子鉴定案件中获取统计信息的重要手段。因此,对于被错误指控的父亲,排除父权或有力证据反对父权的总体概率为18.7%。基于1316例亲子鉴定案件的资料,得出结论:在亲子鉴定有争议的案件中,GPT系统是其他遗传标记系统的重要补充。

相似文献

1
Application of the GPT system in paternity cases.GPT系统在亲子鉴定案件中的应用。
Hum Hered. 1975;25(3):204-17. doi: 10.1159/000152727.
2
Glutamate-pyruvate transaminase (GPT) variant found in a disputed paternity case.在一宗有争议的亲子鉴定案中发现的谷氨酸丙酮酸转氨酶(GPT)变异体。
Tohoku J Exp Med. 1987 Dec;153(4):383-8. doi: 10.1620/tjem.153.383.
3
Comparative studies on the human glutamate-pyruvate transaminase phenotypes--GPT 1, GPT 2-1, GPT 2.
Humangenetik. 1975 Sep 20;30(3):237-49. doi: 10.1007/BF00279189.
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[GPT system, with special reference to the silent gene GPT].[谷丙转氨酶系统,特别提及沉默基因谷丙转氨酶]
Humangenetik. 1973;18(4):341-8. doi: 10.1007/BF00291132.
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[Forensic importance of spectrophotometric tests of the isoenzyme systems red cell acid phosphatase and glutamatic-pyruvic transaminase in settlement of paternity disputes (author's transl)].[红细胞酸性磷酸酶和谷丙转氨酶同工酶系统分光光度法检测在亲子关系纠纷解决中的法医学重要性(作者译)]
Z Rechtsmed. 1974 Jun 18;74(3):177-80. doi: 10.1007/BF00200586.
6
[Supplement to the expert opinion about the value of quantitative studies of the isoenzymes erythrocyte acid phosphatase and GPT].[红细胞酸性磷酸酶和谷丙转氨酶同工酶定量研究价值的专家意见补充]
Z Rechtsmed. 1975 Nov 28;76(3):235-8.
7
[Reply to Ritter's critique of the study "Foresenic value of quantitative studies of the isoenzymes erythrocyte acid phosphatase and glutamic-pyruvic transaminase (GPT) in the clarification of disputed parentage" as well as a discussion of the expert opinion].[对里特对“红细胞酸性磷酸酶和谷丙转氨酶(GPT)定量研究在亲子鉴定中的法医价值”研究的批评的回复以及专家意见的讨论]
Z Rechtsmed. 1975 Nov 28;76(3):239-43. doi: 10.1007/BF00201224.
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[Inheritance of the gene GPT3 of erythrocyte-GPT (E.C.2.6.1.2) in 4 Berlin families].[4个柏林家族中红细胞谷丙转氨酶(E.C.2.6.1.2)基因GPT3的遗传]
Blut. 1973 Jul;27(1):59-61. doi: 10.1007/BF01631427.
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Red cell glutamate-pyruvate transaminase in studies of paternity cases in the United Kingdom.英国亲子鉴定案例研究中的红细胞谷丙转氨酶
Forensic Sci. 1974 Feb;3(1):39-43. doi: 10.1016/0300-9432(74)90005-3.
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Distribution of GPT types in Norway.挪威GPT类型的分布情况。
Hum Hered. 1975;25(1):20-9. doi: 10.1159/000152704.

引用本文的文献

1
Glutamic pyruvic transaminase and esterase D types in the Asian-Pacific area.亚太地区的谷丙转氨酶和酯酶D类型。
Hum Genet. 1976 Dec 29;35(1):91-102. doi: 10.1007/BF00295623.
2
Localization of HLA on the short arm of chromosome 6.人类白细胞抗原(HLA)在6号染色体短臂上的定位。
Hum Genet. 1977 Jun 30;37(2):131-9. doi: 10.1007/BF00393575.