Goldobenko G V, Stroganova L G, Firsova P P, Iliukhin S A, Konovalova V V
Vopr Onkol. 1979;25(12):67-71.
The results of using large fractionation irradiation preoperatively in 131 breast cancer patients are reported. A focal dosage for a primary tumor was found to be 2400 rad (1350 ret) and 1800 rad (1100 ret) for axillary lymph nodes, which given by 600 rad in a day neither effect the course of surgical intervention nor increase the number of the postoperative complications. A five-year cure with stage I-II was 66,3 +/- 11,1%, with stage III--47,9 +/- 7,3%. The whole course of radical treatment lasted on the average for 41-46 days.
报告了131例乳腺癌患者术前使用大分割照射的结果。发现原发肿瘤的局部剂量为2400拉德（1350伦琴当量物理剂量），腋窝淋巴结为1800拉德（1100伦琴当量物理剂量），每天给予600拉德既不影响手术干预进程，也不增加术后并发症的数量。I-II期患者的五年治愈率为66.3±11.1%，III期患者为47.9±7.3%。根治性治疗的整个疗程平均持续41-46天。
