Vásquez-Molina M E, Corral-Terrazas M, Apezteguia M A, Carmona-Sawasky J, Levario-Carrillo M
Laboratorio de Análisis Clínicos de la Unidad de Medicina Familiar 44 del Instituto Mexicano del Seguro Social, Avenida Tecnológico y C. Pino S/N colonia Granjas Chihuahua, 31160 Chihuahua, México.
Salud Publica Mex. 2001 Sep-Oct;43(5):402-7.
To establish the relationship of normal, low, and moderate blood iron values in mothers and their newborns.
A cross-sectional study was conducted among 163 pregnant women and their newborns, users of Hospital de Ginecología y Obstetricia número 15, Instituto Mexicano del Seguro Social, from Chihuahua, Mexico. The mothers' clinical histories were collected and analyzed; hemoglobin, hematocrit, and ferritin serum levels were measured in maternal and umbilical cord samples. Iron maternal stores were determined by ferritin (microgram/l) values as follows: low: < or = 11; moderate: 12-20; and normal: > or = 20.1. The Kruskal-Wallis test was used to establish differences among group; the chi-squared test to determine differences of proportions; and Pearson's correlation coefficient for assessing the association between maternal and newborn iron stores.
A weak correlation between maternal and neonatal ferritin was found (r = 0.14, p = 0.07). Geometric means of neonatal ferritin for low, moderate, and normal maternal iron stores were 4.77, 4.85, and 5.02 respectively (p = 0.12). The maternal iron stores changed after iron supplementation (p = 0.01).
Iron stores in mothers and their newborns are closely related. Women who take iron supplements during pregnancy have significantly higher iron stores at the end of pregnancy.
建立母亲及其新生儿正常、低和中等血液铁值之间的关系。
对墨西哥奇瓦瓦州墨西哥社会保障局第15号妇产科医院的163名孕妇及其新生儿进行了一项横断面研究。收集并分析了母亲的临床病史;测量了母亲和脐带样本中的血红蛋白、血细胞比容和血清铁蛋白水平。根据铁蛋白(微克/升)值确定母亲的铁储备如下:低:≤11;中等:12 - 20;正常:≥20.1。采用Kruskal - Wallis检验确定组间差异;采用卡方检验确定比例差异;采用Pearson相关系数评估母亲和新生儿铁储备之间的关联。
发现母亲和新生儿铁蛋白之间存在弱相关性(r = 0.14,p = 0.07)。母亲铁储备低、中等和正常时,新生儿铁蛋白的几何平均值分别为4.77、4.85和5.02(p = 0.12)。补充铁剂后母亲的铁储备发生了变化(p = 0.01)。
母亲及其新生儿的铁储备密切相关。孕期服用铁补充剂的女性在妊娠末期的铁储备显著更高。