Roggeman S, Zaman Z
Department of Laboratory Medicine, University Hospital Leuven, Belgium.
Am J Clin Pathol. 2001 Dec;116(6):872-8. doi: 10.1309/GRT7-Q6WP-VGWE-0YUM.
We aimed to reduce the number of manual urine microscopy examinations safely by cross-interpretation of the Sysmex UF-100 (TOA Medical Electronics, Kobe, Japan) and urine strip results such that microscopy would be performed if there was discordance between the UF-100 and urine strip results. We also evaluated the usefulness of the optional UF-100 expert software. We performed 2 studies: study 1 to establish review rules for eventual microscopic examination; study 2, a validation study. Our review rates were 40% and 48% and those of UF-100 software were 16% and 32% for the 2 studies. Our false-positive and false-negative results, among the samples not flagged for microscopic review, were acceptably low. We did not find a good correlation between the microscopic classification of RBC morphologic features and the classification given by the UF-100. Since incorporation of the automated urine strip reader and the UF-100 in routine use, our manual microscopy has been reduced to less than 40%.
我们旨在通过对Sysmex UF - 100（日本神户东亚医疗电子公司）和尿试纸结果进行交叉解读，安全地减少人工尿液显微镜检查的次数，以便在UF - 100和尿试纸结果不一致时进行显微镜检查。我们还评估了可选的UF - 100专家软件的实用性。我们进行了两项研究：研究1用于建立最终显微镜检查的复查规则；研究2为验证性研究。两项研究中我们的复查率分别为40%和48%，UF - 100软件的复查率分别为16%和32%。在未标记进行显微镜复查的样本中，我们的假阳性和假阴性结果低至可接受水平。我们未发现红细胞形态特征的显微镜分类与UF - 100给出的分类之间存在良好的相关性。自从将自动尿试纸读取器和UF - 100纳入常规使用以来，我们的人工显微镜检查已减少到不到40%。
