Wai E K, Davis A M, Griffin A, Bell R S, Wunder J S
University of Toronto, Ontario, Canada.
Clin Orthop Relat Res. 2001 Dec(393):279-86. doi: 10.1097/00003086-200112000-00032.
Pathologic fractures of the proximal femur secondary to benign bone tumors often are difficult to treat because of specific anatomic features of this region and the aggressiveness of the tumors. Between 1986 and 1996, 11 patients presented with a pathologic fracture of the proximal femur secondary to a benign bone tumor. All were treated with a uniform approach consisting of biopsy, intralesional curettage, high-speed burring, and reconstruction using morselized allograft, autograft, and a fixed-angle implant. The average followup was 4 years 3 months (range, 24-114 months). One patient was lost to followup. All fractures healed, and there were no local recurrences and no cases of avascular necrosis. Functional evaluation revealed generally good results. Patients scored a mean of 32.6 on the original Musculoskeletal Tumor Society scale and 95.8 on the revised version. The average Toronto Extremity Salvage Score was 91.3. With the numbers available, there were no significant differences between the study group and population norms in the Short Form-36. These results suggest that a uniform approach based on preservation of the femoral head can be applied successfully to the treatment of these lesions with good local tumor control, fracture healing, and acceptable functional outcomes.
继发于良性骨肿瘤的股骨近端病理性骨折,由于该区域特定的解剖学特征以及肿瘤的侵袭性,往往难以治疗。1986年至1996年间,11例患者出现继发于良性骨肿瘤的股骨近端病理性骨折。所有患者均采用统一的治疗方法,包括活检、病灶内刮除、高速磨钻,以及使用碎骨同种异体骨、自体骨和角稳定型植入物进行重建。平均随访时间为4年3个月(范围24 - 114个月)。1例患者失访。所有骨折均愈合,无局部复发,也无缺血性坏死病例。功能评估显示总体结果良好。患者在原始肌肉骨骼肿瘤学会评分量表上的平均得分为32.6分,在修订版上为95.8分。多伦多肢体挽救评分平均为91.3分。就现有数据而言,研究组与普通人群在简明健康状况调查简表-36上无显著差异。这些结果表明,基于保留股骨头的统一治疗方法可成功应用于这些病变的治疗,能实现良好的局部肿瘤控制、骨折愈合及可接受的功能结果。