Pehrson B, Holmgren N, Trafikowska U
Swedish University of Agricultural Sciences, Department of Animal Environment and Health, Skara.
J Vet Med A Physiol Pathol Clin Med. 2001 Nov;48(9):569-75. doi: 10.1046/j.1439-0442.2001.00390.x.
The main aim of the study was to test if parenteral administration of alpha-tocopheryl acetate twice before farrowing and weaning could increase the vitamin E status of the newborn piglets and piglets after weaning. In Trial I eight sows were given 1.5 g alpha-tocopheryl acetate intramuscularly 7 and 2 days before farrowing. Eight sows were untreated controls. The experimental sows had a higher vitamin E concentration in colostrum than the controls. No significant difference between the groups existed in milk at weaning. The serum vitamin E concentration in the experimental piglets 2 and 5 days after farrowing was higher than in the controls. Fifteen days after farrowing the difference between the groups had nearly disappeared. The serum vitamin E concentration in the piglets in the control group was higher during the first days after farrowing than later, and was gradually reduced until at least 2 weeks after weaning. In Trial II, eight sows were given 1.5 g of alpha-tocopheryl acetate 7 and 2 days before weaning of their piglets. They had higher vitamin E concentrations in milk and serum than untreated control sows at weaning. The increase did not, however, influence the serum vitamin E concentration of the piglets. The lowest concentration of vitamin E in serum of the piglets was reached at 45 days after farrowing. The activity of the selenium-dependent enzyme glutathione peroxidase in the serum of piglets was very low during the first week of life in both groups despite the fact that the sows' feed had been supplemented with 0.35 mg selenium/kg. This indicates that the selenium status of newborn piglets might be more critical for their health than their vitamin E status.
本研究的主要目的是测试在分娩和断奶前两次肠胃外注射醋酸生育酚是否能提高新生仔猪和断奶后仔猪的维生素E水平。在试验I中，八头母猪在分娩前7天和2天分别肌肉注射1.5克醋酸生育酚。八头母猪作为未处理的对照。试验母猪初乳中的维生素E浓度高于对照母猪。断奶时两组母猪的乳汁中维生素E浓度无显著差异。试验仔猪在分娩后2天和5天的血清维生素E浓度高于对照仔猪。分娩后15天，两组之间的差异几乎消失。对照组仔猪在分娩后的头几天血清维生素E浓度高于后期，并逐渐降低，直至断奶后至少2周。在试验II中，八头母猪在其仔猪断奶前7天和2天分别注射1.5克醋酸生育酚。断奶时，它们乳汁和血清中的维生素E浓度高于未处理的对照母猪。然而，这种增加并未影响仔猪的血清维生素E浓度。仔猪血清中维生素E的最低浓度在分娩后45天达到。尽管母猪饲料中添加了0.35毫克硒/千克，但两组仔猪出生后第一周血清中硒依赖性酶谷胱甘肽过氧化物酶的活性都非常低。这表明新生仔猪的硒水平对其健康可能比维生素E水平更为关键。
