Rubinstein P, Morales M, Pandiani A, Bagattini J C
Departamento de Medicina, Hospital Pasteur, Montevideo, Uruguay.
Acta Gastroenterol Latinoam. 2001 Oct;31(4):307-12.
Spontaneous bacterial peritonitis (SBP) is a frequent and severe complication of cirrhotic patients with ascites. In order to analyze the incidence, bacteriology and in-hospital mortality, we studied 64 consecutive patients with cirrhosis and ascites (47 males, 17 females average age 59 years) hospitalized in a general adults 3rd level hospital (Pasteur hospital, Montevideo, Uruguay), between September 1998 and May 2000. The diagnostic criteria was more than 250 polymorphonuclear cells/cu.mm. in ascitic fluid and/or a positive culture. We found 17 SBP in 17 patients (10 males 24-81 years) which means an incidence of 26.56%. 15 alcoholic cirrhosis and 2 autoimmune disease. 12% (2/17) were asymptomatic; 8/17 were SBP culture positive (5 E. Coli, 2 St. Pneumoniae, 1 Klebsiella sp.), and 9 were culture negative. The mortality rate associated with SBP was 47% (8/17), greater than the cirrhotic group without SBP (12.7% p < 0.01).
自发性细菌性腹膜炎（SBP）是肝硬化腹水患者常见且严重的并发症。为分析其发病率、细菌学特征及住院死亡率，我们对1998年9月至2000年5月期间在乌拉圭蒙得维的亚巴斯德医院（一家普通成人三级医院）住院的64例连续性肝硬化腹水患者（47例男性，17例女性，平均年龄59岁）进行了研究。诊断标准为腹水多形核细胞计数超过250个/立方毫米和/或培养阳性。我们在17例患者（10例男性，年龄24 - 81岁）中发现了17例SBP，发病率为26.56%。其中15例为酒精性肝硬化，2例为自身免疫性疾病。12%（2/17）无症状；17例中有8例SBP培养阳性（5例大肠杆菌、2例肺炎链球菌、1例克雷伯菌属），9例培养阴性。SBP相关的死亡率为47%（8/17），高于无SBP的肝硬化组（12.7%，p < 0.01）。
