DeHaas R A, Calamari J E, Bair J P, Martin E D
Department of Psychology, Finch University of Health Sciences, The Chicago Medical School, North Chicago, IL 60064, USA.
Addict Behav. 2001 Nov-Dec;26(6):787-801. doi: 10.1016/s0306-4603(01)00237-4.
Anxiety sensitivity (AS) has been linked to both pathological anxiety and substance use problems. We evaluated relations between AS and substance use situations among individuals with substance use disorders (SUDs) and concurrent DSM-IV anxiety disorders. We predicted that AS would be most strongly associated with substance use in situations involving negative emotions and interpersonal conflict in substance abusers with anxiety disorders. This group was compared to substance abusers with concurrent mood disorders and substance abusers without other disorders (N=88). AS was positively related to negative emotion situations substance use for substance abusers with anxiety disorders and for substance abusers without other disorders. Contrary to predictions, significant differences between these groups were not found. The relationship between AS and negative emotion situations substance use remained after controlling trait anxiety in a combined group (anxiety disorders and substance abuse only groups). AS did not predict substance use for participants with concurrent mood disorders. Identification of factors that place anxious patients at risk for substance use problems will have implications for treatment and for the prevention of this form of maladaptive coping.
焦虑敏感性（AS）与病理性焦虑和物质使用问题都有关联。我们评估了物质使用障碍（SUDs）患者以及并发DSM-IV焦虑症的个体中，AS与物质使用情境之间的关系。我们预测，在患有焦虑症的药物滥用者中，AS与涉及负面情绪和人际冲突的情境中的物质使用关联最为紧密。将这组人与并发情绪障碍的药物滥用者以及无其他障碍的药物滥用者（N = 88）进行比较。对于患有焦虑症的药物滥用者以及无其他障碍的药物滥用者，AS与负面情绪情境下的物质使用呈正相关。与预测相反，未发现这些组之间存在显著差异。在合并组（仅焦虑症和药物滥用组）中控制特质焦虑后，AS与负面情绪情境下物质使用之间的关系依然存在。AS无法预测并发情绪障碍参与者的物质使用情况。识别使焦虑患者面临物质使用问题风险的因素，将对治疗以及预防这种适应不良的应对形式具有重要意义。
