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[血液透析患者的舒张功能障碍]

[Disorders of diastolic function in patients on hemodialysis].

作者信息

Nuhbegovic S, Halibasic A, Ljuca F, Karamehic J, Meric M, Terzic I

机构信息

Zavod za fiziologiju Medicinskog fakulteta u Tuzli.

出版信息

Med Arh. 2001;55(4):219-20.

Abstract

INTRODUCTION

Impaired cardiac function is frequently present in patients on maintenance haemodialysis.

AIM

To assess the left ventricular diastolic function in patients on haemodialysis.

MATERIAL AND METHODS

We used 2D and pulsed wave Doppler echocardiography to evaluate the left ventricular diastolic function in 40 patients on haemodialysis and compared those to healthy controls.

RESULTS

Majority of Doppler parameters were changed in patients on haemodialysis. Diastolic dysfunction was present in 77.5% patients. In comparison to the healthy controls haemodialysis patients showed significant increase in peak velocity of late diastolic filling, (A wave, 76.82 +/- 23.76 cm/s vs. 58.46 +/- 9.65 cm/s p < 0.001) and reduction in the E/A ratio (1.00 +/- 0.26 vs. 1.26 +/- 0.31 p < 0.001).

CONCLUSION

There was significant impairment in left ventricular diastolic function in patients on haemodialysis.

摘要

引言

维持性血液透析患者常出现心脏功能受损。

目的

评估血液透析患者的左心室舒张功能。

材料与方法

我们使用二维和脉冲波多普勒超声心动图评估40例血液透析患者的左心室舒张功能,并将其与健康对照者进行比较。

结果

血液透析患者的大多数多普勒参数发生了变化。77.5%的患者存在舒张功能障碍。与健康对照者相比,血液透析患者舒张晚期充盈峰值速度显著增加(A波,76.82±23.76cm/s对58.46±9.65cm/s,p<0.001),E/A比值降低(1.00±0.26对1.26±0.31,p<0.001)。

结论

血液透析患者左心室舒张功能存在显著损害。

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