Liu R, Gullane P, Brown D, Irish J
The Toronto General Hospital, University Health Network, Ontario.
J Otolaryngol. 2001 Feb;30(1):34-40. doi: 10.2310/7070.2001.21011.
The pectoralis major myocutaneous pedicled flap (PMMPF) has been considered to be the "workhorse" of pedicled flaps for head and neck reconstruction, and several series of PMMPF procedures have been reported in the literature. Between 1983 and 1997, 244 reconstruction procedures using the PMMPF were carried out on 229 patients by the Otolaryngology-Head and Neck Surgery Department at the Toronto General Hospital. Pectoralis major myocutaneous pedicled flap reconstructions were completed after ablation of cancer in the following sites: oral cavity, 113; oropharynx/hypopharynx, 50; larynx, 59; and other, 21. The locations of reconstruction were oral cavity, 121; pharynx, 74; and neck or face, 50. Of the 244 cases, 202 were carried out as primary reconstructive procedures, whereas 42 flaps were "salvage" procedures (reconstruction after fistula, flap failure, osteoradionecrosis, and internal jugular vein rupture). Eighty-five cases (35%) were affected by complications such as dehiscence, infection, hematoma, seroma, partial flap failure, total flap failure, fistula, and donor site complications. The duration of admission for cases with complications was longer, and higher complication rates were associated with salvage procedures, number of comorbidities, number of pack-years of cigarettes smoked, and oral cavity reconstructions. This series of consecutive PMMPF procedures is the largest reported to date.
胸大肌肌皮蒂瓣(PMMPF)一直被认为是头颈重建带蒂皮瓣中的“主力”,文献中已有多篇关于PMMPF手术系列的报道。1983年至1997年间,多伦多总医院耳鼻咽喉头颈外科对229例患者实施了244例使用PMMPF的重建手术。胸大肌肌皮蒂瓣重建手术在以下部位的癌症切除术后完成:口腔,113例;口咽/下咽,50例;喉,59例;其他,21例。重建部位为口腔,121例;咽部,74例;颈部或面部,50例。在这244例病例中,202例为一期重建手术,而42例皮瓣为“挽救性”手术(瘘管形成、皮瓣失败、放射性骨坏死和颈内静脉破裂后的重建)。85例(35%)出现了诸如裂开、感染、血肿、血清肿、部分皮瓣失败、完全皮瓣失败、瘘管和供区并发症等并发症。出现并发症的病例住院时间更长,更高的并发症发生率与挽救性手术、合并症数量、吸烟包年数和口腔重建有关。这一系列连续的PMMPF手术是迄今为止报道的最大规模的。