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儿童虐待和精神病理学对神经内分泌功能的影响。

The impact of child maltreatment and psychopathology on neuroendocrine functioning.

作者信息

Cicchetti D, Rogosch F A

机构信息

Mt Hope Family Center, University of Rochester, NY 14608, USA.

出版信息

Dev Psychopathol. 2001 Fall;13(4):783-804.

PMID:11771908
Abstract

Cortisol regulation was investigated in a sample of school-aged maltreated (n = 167) and demographically comparable low-income nonmaltreated (n = 204) boys and girls in the context of a day camp research program. The presence of clinical-level internalizing and clinical-level externalizing symptomatology was determined through adult report and child self report. Children who exhibited clinical-level internalizing problems only, clinical-level externalizing problems only, and comorbid clinical-level internalizing and extemalizing problems were identified. Clinical-level cases were more prevalent among the maltreated children. Maltreated children with clinical-level internalizing problems were distinguished by higher morning, afternoon, and average daily cortisol levels across the week of camp attendance. In contrast, nonmaltreated boys with clinical-level externalizing problems emerged as distinct in terms of low levels of morning and average daily levels of cortisol. Maltreated children with comorbid clinical-level internalizing and externalizing problems were more likely not to show the expected diumal decrease in cortisol. The findings are discussed in terms of the joint impact of maltreatment and different forms of psychopathology on neuroendocrine regulation.

摘要

在一个日间夏令营研究项目中,对一组学龄期受虐待儿童(n = 167)以及在人口统计学特征上与之匹配的低收入非受虐待儿童(n = 204)进行了皮质醇调节情况的调查。通过成人报告和儿童自我报告来确定临床水平的内化症状和临床水平的外化症状是否存在。识别出仅表现出临床水平内化问题、仅表现出临床水平外化问题以及同时存在临床水平内化和外化问题的儿童。临床水平的病例在受虐待儿童中更为普遍。在参加夏令营的整周时间里,有临床水平内化问题的受虐待儿童的特点是早晨、下午及平均每日皮质醇水平较高。相比之下,有临床水平外化问题的非受虐待男孩则表现为早晨皮质醇水平低以及平均每日皮质醇水平低。同时存在临床水平内化和外化问题的受虐待儿童更有可能未表现出预期的皮质醇昼夜下降。从虐待与不同形式精神病理学对神经内分泌调节的联合影响方面对研究结果进行了讨论。

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