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全科医生如何评估使用新药的风险。

How general practitioners assess risks in using new drugs.

作者信息

Williamson P M

出版信息

J R Coll Gen Pract. 1975 May;25(154):383-6.

Abstract

;Situational' risk is an important determinant in the adoption of new pharmaceuticals. Not specifically the scientific risk of using the drug, but rather the risk the doctor perceives through his previous experience, both with similar treatments and with factors associated with the innovation such as its sponsor and mode of action. With this information the doctor determines to what degree further validation is required in order to allay any fears. The extent and complexity of this additional reassurance will thus determine how long is required before adoption and to what extent additional sources of information should be consulted.

摘要

情境风险是新药物采用过程中的一个重要决定因素。并非特指使用该药物的科学风险,而是医生通过其以往经验所感知到的风险,这既包括类似治疗的经验,也包括与创新相关的因素,如药物赞助商和作用方式。基于这些信息,医生确定需要进一步验证到何种程度以消除任何疑虑。这种额外保证的范围和复杂性将因此决定采用前所需的时间以及应参考其他信息来源的程度。

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