在戒烟治疗后检测是否复吸。

Detecting smoking following smoking cessation treatment.

作者信息

Gariti Peter, Alterman Arthur I, Ehrman Ronald, Mulvaney Francis D, O'Brien Charles P

机构信息

Department of Psychiatry, Treatment Research Center, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104, USA.

出版信息

Drug Alcohol Depend. 2002 Jan 1;65(2):191-6. doi: 10.1016/s0376-8716(01)00162-4.

DOI:10.1016/s0376-8716(01)00162-4

PMID:11772480

Abstract

Our study compared the results of self-report (SR) plus breath carbon monoxide (CO) monitoring to SR plus urine cotinine (COT) analysis of recent tobacco use for a recently completed smoking cessation study that compared the efficacy of different intensities of psychosocial treatments coupled with 8 weeks of patch treatment. Treatment outcomes were assessed 9, 26, and 52 weeks from treatment initiation in 200+ patients using both measurement types. COT was able to detect self-reported smoking in over 97% of the cases at all time points, while CO detected self-reported smoking 62, 84, and 89% of the time for the three follow-up assessments. Under 2% of those reporting nonsmoking were found to be smoking via CO, whereas COT found smoking to have occurred for 23, 15, and 7% of the 'nonsmoking' SRs at the three time points. Abstinence rates using SR plus CO were 49, 29, and 26%, contrasted with abstinence rates of 38, 26, and 25% for SR plus COT. These findings suggest that use of urine analysis for COT may lead to more accurate but lowered measured abstinence rates.

摘要

在一项刚刚完成的戒烟研究中，我们的研究比较了自我报告（SR）加呼气一氧化碳（CO）监测与SR加尿液可替宁（COT）分析在近期烟草使用情况方面的结果。该戒烟研究比较了不同强度心理社会治疗与8周贴片治疗相结合的疗效。在200多名患者中，从治疗开始后的第9周、26周和52周，使用这两种测量方法评估治疗结果。在所有时间点，COT能够在超过97%的病例中检测到自我报告的吸烟情况，而在三次随访评估中，CO检测到自我报告吸烟情况的时间分别为62%、84%和89%。在报告不吸烟的人群中，通过CO检测发现吸烟的比例不到2%，而在三个时间点，COT发现“不吸烟”的自我报告中有23%、15%和7%的人实际吸烟。使用SR加CO的戒烟率分别为49%、29%和26%，而SR加COT的戒烟率分别为38%、26%和25%。这些发现表明，使用尿液分析检测COT可能会得出更准确但测得的戒烟率较低的结果。