Lohrmann R, Ranganathan R, Sawai H, Orgel L E
J Mol Evol. 1975 Jun 9;5(1):57-73. doi: 10.1007/BF01732014.
The reactions of benzoate ion and of glycine with adenosine 5-phosphorimidazolide have been investigated. Benzoate reacts first to give the anhydride, benzoyl-adenylate, which, in the presence of excess imidazole, reacts further to give the 2'- and 3'-esters of adenosine 5'-phosphate. Glycine also first attacks the imidazolide to give an anhydride, but this compound may react further either to give 2- and 3'-esters or to form peptides, depending on the reaction conditions.
已对苯甲酸根离子和甘氨酸与腺苷5 - 磷酰咪唑的反应进行了研究。苯甲酸首先反应生成酸酐，即苯甲酰腺苷酸，在过量咪唑存在下，它会进一步反应生成腺苷5'-磷酸的2'-酯和3'-酯。甘氨酸也首先进攻咪唑化物生成酸酐，但根据反应条件，该化合物可能进一步反应生成2'-酯和3'-酯，或者形成肽。
