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固态下益生元肽的形成。III. 甘氨酸在含有无机多聚磷酸盐的固态混合物中的缩合反应。

Prebiotic peptide-formation in the solid state. III. Condensation reactions of glycine in solid state mixtures containing inorganic polyphosphates.

作者信息

Sawai H, Orgel L E

出版信息

J Mol Evol. 1975 Nov 4;6(3):185-97. doi: 10.1007/BF01732355.

DOI:10.1007/BF01732355
PMID:1539
Abstract

The reactions of glycine with inorganic polyphosphates in the solid state have been studied. The formation of peptides up to the decamer occurs at moderate temperatures(r.t.-100 degrees C) in the presence of imidazole and magnesium chloride. If adenosine 5' -monophosphate is added to the reaction mixture, 2'(3') -o-glycyl adenosine 5'-monophosphate is also obtained. These reactions could have occurred on the primitive earth.

摘要

已经研究了甘氨酸与固态无机多磷酸盐的反应。在咪唑和氯化镁存在下，在中等温度（室温至100摄氏度）下会形成直至十聚体的肽。如果将5'-单磷酸腺苷添加到反应混合物中，还会得到2'（3'）-O-甘氨酰-5'-单磷酸腺苷。这些反应可能在原始地球上发生过。

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Prebiotic peptide-formation in the solid state. I. Reactions of benzoate ion and glycine with adenosine 5'-phosphorimidazolide.固态下的益生元肽形成。I. 苯甲酸根离子和甘氨酸与腺苷5'-磷酰咪唑的反应。
J Mol Evol. 1975 Jun 9;5(1):57-73. doi: 10.1007/BF01732014.
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J Mol Evol. 1975 Nov 4;6(3):165-84. doi: 10.1007/BF01732354.