[单囊性成釉细胞瘤的临床病理及凝集素免疫组织化学研究]
[A study of clinicopathology and lectin immunohistochemistry in unicystic ameloblastoma].
作者信息
Wang Y, Wang S, Chen X
机构信息
School of Stomatology, Hubei Medical University, Wuhan 430079.
出版信息
Zhonghua Kou Qiang Yi Xue Za Zhi. 1999 Jul;34(4):226-8.
OBJECTIVE
To investigate clinicopathological characteristics of unicystic ameloblastoma and histological markers for differential diagnosis with odontogenic cyst.
METHODS
HE staining and histopathological observation, and lectin UEA-1, BSA-1 immunohistochemistry staining.
RESULTS
40 cases of unicystic ameloblastoma were divided histologically into 3 groups. In odontogenic cysts, most of epithelial lining showed positive binding with UEA-1 and BSA-1, whereas negative reactions were obtained for these two lectins in the epithelial components of unicystic ameloblastoma and solid or multicystic ameloblastoma, except for limited UEA-1 or BSA-1 binding to markedly keratinized tumor cells in several cases of ameloblastomas.
CONCLUSION
The unicystic ameloblastoma is a distinct entity which has characteristic clinicopathology. The lectin staining for UEA-1 and BSA-1 is a useful histological aid to differential diagnosis between unicystic ameloblastoma and odontogenic cyst.
目的
探讨单囊型成釉细胞瘤的临床病理特征及与牙源性囊肿鉴别诊断的组织学标志物。
方法
进行苏木精-伊红（HE）染色及组织病理学观察，以及荆豆凝集素-1（UEA-1）、大豆凝集素-1（BSA-1）免疫组织化学染色。
结果
40例单囊型成釉细胞瘤在组织学上分为3组。在牙源性囊肿中，大多数上皮衬里与UEA-1和BSA-1呈阳性结合，而在单囊型成釉细胞瘤及实性或多囊型成釉细胞瘤的上皮成分中，这两种凝集素呈阴性反应，除了在几例成釉细胞瘤中，有限的UEA-1或BSA-1与明显角化的肿瘤细胞结合。
结论
单囊型成釉细胞瘤是一种具有特征性临床病理的独特实体。UEA-1和BSA-1的凝集素染色是单囊型成釉细胞瘤与牙源性囊肿鉴别诊断的有用组织学辅助手段。
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