Li Tiejun, Wu Yuntang, Yu Shifeng, Yu Guangyan
Department of Oral Pathology, Peking University School of Stomatology, Beijing 100081, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2002 May;37(3):210-2.
To clarify the clinicopathological spectrum and biologic behavior of unicystic ameloblastomas (UA).
Retrospective analysis of 33 UA was undertaken to relate clinicopathological variables to recurrence.
The clinical features of this series were in general agreement with that of the previous reports. UA tended to occur at an earlier age (mean 25.3 years), with a male predilection and predominant mandibular involvement (90.9%). Microscopically, the tumors demonstrated a generally monocystic growth pattern, with 8 being simple cystic, 10 comprising intraluminal nodules, and 15 exhibiting a conspicuous component of infiltrative tumor islands in the cyst capsule. Follow-up of 29 patients revealed 6 recurrences with an average interval of 7 years. Recurrence also related to histologic subtypes of UA, with those invading the fibrous wall having a rate of 35.7% but others 6.7%.
Despite the fact that unicystic ameloblastoma may, in general, compare favorably with its solid or multicystic counterpart in terms of clinical behavior and response to treatment, the subsets of the maxillary lesions or tumors exhibiting mural invasion could have a high risk of recurrence.
明确单囊型成釉细胞瘤（UA）的临床病理特征及生物学行为。
对33例UA进行回顾性分析，以探讨临床病理变量与复发的关系。
本系列病例的临床特征与既往报道基本一致。UA倾向于在较年轻的年龄发生（平均25.3岁），男性多见，主要累及下颌骨（90.9%）。显微镜下，肿瘤通常呈单囊生长模式，其中8例为单纯囊性，10例有腔内结节，15例在囊壁有明显的浸润性肿瘤岛成分。对29例患者的随访显示6例复发，平均复发间隔为7年。复发还与UA的组织学亚型有关，侵犯纤维壁的复发率为35.7%，而其他亚型为6.7%。
尽管总体而言，单囊型成釉细胞瘤在临床行为和对治疗的反应方面可能优于实性或多囊型成釉细胞瘤，但上颌病变或表现为壁内侵犯的肿瘤亚组可能具有较高的复发风险。
