Nie J, Liu S, Di L
School of Oncology, Beijing University, Beijing 100036, China.
Zhonghua Zhong Liu Za Zhi. 2000 Sep;22(5):432-4.
To study cancer pain and its effect on cancer patients' quality of life.
Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and Brief Pain Inventory (BPI) methods were used to investigate cancer pain, its effect on patients' quality of life and management in 200 cancer inpatients.
The incidence of cancer pain was 69%, including 21.5% with mild pain, 19% with moderate pain and 28.5% with severe pain. Moderate and severe pain occurred more frequently in patients with cancer of the digestive tract. No correlation was found between pain and stage of the disease, but was closely associated with bone metastasis. Regardless of its severity, cancer pain seriously affected patients general activity, mood, walking ability, normal work and sleep. With the seriousness of pain, the patients were more affected. However, there was no obvious difference between moderate and severe pain in terms of their effect on the patients' joy of life and relations with people. The effect of moderate pain on patients' mentality appeared earlier than did severe pain. Among patients with cancer pain, 41.3% of them did not receive proper treatment. Only 52.1% of patients with severe pain were given strong opioids, which is far from the anti-pain standard set forth by the WHO.
Cancer pain is one of the most important factors which affect cancer patients' quality of life. For adequate control of cancer pain, there is still a long way to go to achieve WHO's goal.
研究癌症疼痛及其对癌症患者生活质量的影响。
采用医学结局研究简明健康调查量表（SF - 36）和简明疼痛问卷（BPI）方法，对200例癌症住院患者的癌症疼痛、其对患者生活质量的影响及管理情况进行调查。
癌症疼痛发生率为69%，其中轻度疼痛占21.5%，中度疼痛占19%，重度疼痛占28.5%。中度和重度疼痛在消化道癌症患者中更常见。疼痛与疾病分期无相关性，但与骨转移密切相关。无论疼痛程度如何，癌症疼痛均严重影响患者的日常活动、情绪、行走能力、正常工作和睡眠。随着疼痛程度加重，患者受影响程度更大。然而，中度和重度疼痛对患者生活乐趣和人际关系的影响无明显差异。中度疼痛对患者心理的影响比重度疼痛出现得更早。在癌症疼痛患者中，41.3%未得到恰当治疗。重度疼痛患者中仅52.1%使用了强阿片类药物，远未达到世界卫生组织制定的镇痛标准。
癌症疼痛是影响癌症患者生活质量的最重要因素之一。要充分控制癌症疼痛，实现世界卫生组织的目标仍有很长的路要走。
