Ambros V
Department of Genetics, Dartmouth Medical School, Hanover, NH 03755, USA.
Cell. 2001 Dec 28;107(7):823-6. doi: 10.1016/s0092-8674(01)00616-x.
Animal genomes contain an abundance of small genes that produce regulatory RNAs of about 22 nucleotides in length. These microRNAs are diverse in sequence and expression patterns, and are evolutionarily widespread, suggesting that they may participate in a wide range of genetic regulatory pathways.
动物基因组包含大量小基因,这些小基因产生长度约为22个核苷酸的调控RNA。这些微小RNA在序列和表达模式上具有多样性,并且在进化上广泛存在,这表明它们可能参与多种基因调控途径。