DeVito Michael J, Schecter Arnold
National Health and Environmental Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, USA.
Environ Health Perspect. 2002 Jan;110(1):23-8. doi: 10.1289/ehp.0211023.
Over the past several years there has been concern over exposure to dioxins through the use of tampons and other sanitary products. This article describes attempts to estimate dioxin exposures from tampons and infant diapers; we then compare exposure estimates to dietary dioxin exposures. We analyzed four brands of tampons and four brands of infant diapers obtained from commercial establishments in San Francisco, California, for dioxin concentrations. We estimated exposures to dioxins on the basis of a screening level analysis that assumed all dioxins present were completely absorbed. We also estimated exposures by using a more refined analysis that incorporates partition coefficients to estimate bioavailability. None of the products contained 2,3,7,8-tetrachlorodibenzo-p-dioxin, the most potent dioxin, although other dioxins were present at detectable concentrations in all samples. We observed minimal differences in the concentrations of dioxins between 100% cotton and cotton/pulp products. The refined exposure analysis indicates that exposures to dioxins from tampons are approximately 13,000-240,000 times less than dietary exposures. The refined exposure analysis showed that exposure to dioxins from the diet is more than 30,000-2,200,000 times the exposure through diapers in nursing infants. Although dioxins are found in trace amounts in both cotton and pulp sanitary products, exposure to dioxins through tampons and diapers does not significantly contribute to dioxin exposures in the United States.
在过去几年中,人们一直担心通过使用卫生棉条和其他卫生用品接触二噁英。本文描述了估算卫生棉条和婴儿尿布中二噁英暴露量的尝试;然后我们将暴露量估算值与膳食中二噁英的暴露量进行比较。我们分析了从加利福尼亚州旧金山的商业机构获取的四个品牌的卫生棉条和四个品牌的婴儿尿布中的二噁英浓度。我们基于一种筛选水平分析估算二噁英暴露量,该分析假定所有存在的二噁英都被完全吸收。我们还使用了一种更精细的分析方法来估算暴露量,该方法纳入分配系数以估算生物利用度。尽管所有样品中都存在其他可检测浓度的二噁英,但没有一种产品含有毒性最强的二噁英——2,3,7,8 - 四氯二苯并 - 对 - 二噁英。我们观察到100%纯棉产品和棉/纸浆产品之间二噁英浓度的差异极小。精细的暴露量分析表明,卫生棉条中二噁英的暴露量比膳食暴露量大约低13000 - 240000倍。精细的暴露量分析表明,膳食中二噁英的暴露量是哺乳期婴儿通过尿布接触二噁英量的30000 - 2200000倍以上。尽管在棉和纸浆卫生用品中都发现了痕量的二噁英,但在美国,通过卫生棉条和尿布接触二噁英对二噁英总暴露量的贡献并不显著。