在β-肾上腺素能受体阻断条件下氢化可的松对大鼠腹腔吞噬细胞的影响。
Effects of hydrocortisone on peritoneal phagocytizing cells in rats under conditions of beta-adrenoceptors blockade.
作者信息
Shilov Y I, Lanin D V
机构信息
Laboratory of Ecological Immunology, Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences.
出版信息
Bull Exp Biol Med. 2001 Oct;132(4):987-9. doi: 10.1023/a:1013631714678.
Hydrocortisone decreased the count of peritoneal mononuclear phagocytes and mast cells and total phagocytic activity of peritoneal phagocytes in rats, but had no effect on the nitroblue tetrazolium test. beta-Adrenoceptor blockade abolished the suppressive effect of hydrocortisone on phagocytosis and prevented the decrease in the count of mast cells, but markedly reduced the number of neutrophils and parameters of stimulated nitroblue tetrazolium test.
氢化可的松降低了大鼠腹腔单核吞噬细胞和肥大细胞的数量以及腹腔吞噬细胞的总吞噬活性，但对硝基蓝四唑试验没有影响。β-肾上腺素受体阻断消除了氢化可的松对吞噬作用的抑制效应，并防止了肥大细胞数量的减少，但显著降低了中性粒细胞的数量以及刺激后硝基蓝四唑试验的各项参数。
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