Piazzini A, Canevini M P, Maggiori G, Canger R
Chair of Clinical Neurophysiology, University of Milan, Medical School, Regional Epilepsy Center, S. Paolo Hospital, Milan, Italy.
Eur J Neurol. 2001 Nov;8(6):613-20. doi: 10.1046/j.1468-1331.2001.00287.x.
The aim of the study is to evaluate the correlation between subjective memory complaints and neuropsychological tests in the epilepsy population. We administered a Self Report Memory Questionnaire, based on possible everyday memory failures, two questionnaires on anxiety and depression and a battery of cognitive tests to 150 patients with epilepsy (n=100 with partial epilepsy, n=50 with idiopathic generalized epilepsy) and a control group (n=50). A discrepancy between the results of the memory questionnaire and the cognitive tests was found in the epilepsy patients: the Self Report Memory Questionnaire did not show any correlation with the psychological tests. The same discrepancy was not seen in the controls, where the memory questionnaire was related to two verbal memory tests. Furthermore, patients with epilepsy reported greater difficulties on the Self Report Memory Questionnaire than the controls (P < 0.05). It appeared that the tendency to overstate memory problems was mainly related to anxiety and depression, but was not connected with the type of epilepsy, nor with its duration (in years). Seizure frequency, on the other hand, seemed to greatly influence mood, which in turn is probably affect subjective memory perception.
本研究的目的是评估癫痫患者群体中主观记忆主诉与神经心理学测试之间的相关性。我们对150名癫痫患者（其中100名部分性癫痫患者，50名特发性全身性癫痫患者）和一个对照组（50名）进行了基于日常可能出现的记忆失误的自我报告记忆问卷、两份焦虑和抑郁问卷以及一系列认知测试。在癫痫患者中发现记忆问卷结果与认知测试之间存在差异：自我报告记忆问卷与心理测试未显示出任何相关性。在对照组中未发现同样的差异，在对照组中记忆问卷与两项言语记忆测试相关。此外，癫痫患者在自我报告记忆问卷上报告的困难比对照组更大（P < 0.05）。似乎夸大记忆问题的倾向主要与焦虑和抑郁有关，但与癫痫类型及其病程（以年为单位）无关。另一方面，癫痫发作频率似乎对情绪有很大影响，而情绪反过来可能会影响主观记忆感知。
