Reza K, Talib S, Imam S K
Br Med J. 1979 Oct 13;2(6195):900-1. doi: 10.1136/bmj.2.6195.900.
O-diphenoloxidase activity was studied in 15 patients with lepromatous leprosy, 15 with tuberculois leprosy, and 15 controls. O-diphenoloxidase isolated from skin and serum samples of patients with lepromatous leprosy had the specificity of a bacterially derived enzyme and not that of a mammalian-derived enzyme. Only the patients who had lepromatous leprosy for over two years showed enzyme activity in serum, though all showed it in skin tissue. O-diphenoloxidase activity in serum may be a useful diagnostic marker of lepromatous leprosy.
对15例瘤型麻风患者、15例结核样型麻风患者和15名对照者的邻二酚氧化酶活性进行了研究。从瘤型麻风患者的皮肤和血清样本中分离出的邻二酚氧化酶具有细菌衍生酶的特异性，而非哺乳动物衍生酶的特异性。只有患瘤型麻风超过两年的患者血清中显示出酶活性，不过所有患者的皮肤组织中均显示有该酶活性。血清中的邻二酚氧化酶活性可能是瘤型麻风的一种有用的诊断标志物。
