Lebrun C
Service de Neurologie, Hôpital Pasteur, 30, Voie Romaine, BP69, 06002 Nice.
Rev Neurol (Paris). 2001 Sep;157(8-9 Pt 2):1085-90.
Cognitive impairment and psychiatric disorders occur in about 60 p. cent of multiple sclerosis patients. In general, impairment develops in established cases, although it can present early in the disease course. The pattern of neuropsychological deficits is characterized by deficits in attention, memory and executive functions; No specific treatment seems to be effective in cognitive impairment but appropriate strategies could limit the negative impact on this disease. Depressive states are twice frequent and usual antidepressant drugs seems to demonstrate some efficacy.
